Human Gene PRR11 (uc002ixf.2) Description and Page Index
  Description: Homo sapiens proline rich 11 (PRR11), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr17:57,232,860-57,284,070 Size: 51,211 Total Exon Count: 10 Strand: +
Coding Region
   Position: hg19 chr17:57,247,114-57,278,992 Size: 31,879 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:57,232,860-57,284,070)mRNA (may differ from genome)Protein (360 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIneXtProt
OMIMPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: PRR11_HUMAN
DESCRIPTION: RecName: Full=Proline-rich protein 11;
SEQUENCE CAUTION: Sequence=BAA91064.1; Type=Erroneous initiation;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 16.07 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 34.72 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -99.91312-0.320 Picture PostScript Text
3' UTR -1846.935078-0.364 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q96HE9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Ensembl   
  Protein Sequence   
  Alignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0007050 cell cycle arrest
GO:0051726 regulation of cell cycle

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  AK225380 - Homo sapiens mRNA for hypothetical protein LOC55771 variant, clone: HEP19570.
AK225377 - Homo sapiens mRNA for hypothetical protein LOC55771 variant, clone: HEP18402.
FJ161961 - Homo sapiens transcription repressor of MHCII mRNA, complete cds.
AK001891 - Homo sapiens cDNA FLJ11029 fis, clone PLACE1004156.
BC008669 - Homo sapiens proline rich 11, mRNA (cDNA clone MGC:8798 IMAGE:3867293), complete cds.
AB464073 - Synthetic construct DNA, clone: pF1KB6515, Homo sapiens PRR11 gene for proline rich 11, without stop codon, in Flexi system.
HQ447836 - Synthetic construct Homo sapiens clone IMAGE:100071180; CCSB002848_01 proline rich 11 (PRR11) gene, encodes complete protein.
KJ894259 - Synthetic construct Homo sapiens clone ccsbBroadEn_03653 PRR11 gene, encodes complete protein.
AK000296 - Homo sapiens cDNA FLJ20289 fis, clone HEP04492.
CU679025 - Synthetic construct Homo sapiens gateway clone IMAGE:100019086 5' read PRR11 mRNA.
JD181675 - Sequence 162699 from Patent EP1572962.
JD036374 - Sequence 17398 from Patent EP1572962.
JD303399 - Sequence 284423 from Patent EP1572962.
JD112157 - Sequence 93181 from Patent EP1572962.
JD351803 - Sequence 332827 from Patent EP1572962.
JD201245 - Sequence 182269 from Patent EP1572962.
JD430097 - Sequence 411121 from Patent EP1572962.
JD430099 - Sequence 411123 from Patent EP1572962.
JD430100 - Sequence 411124 from Patent EP1572962.
JD529073 - Sequence 510097 from Patent EP1572962.
JD169106 - Sequence 150130 from Patent EP1572962.
JD566870 - Sequence 547894 from Patent EP1572962.
JD342372 - Sequence 323396 from Patent EP1572962.
JD435394 - Sequence 416418 from Patent EP1572962.
JD385376 - Sequence 366400 from Patent EP1572962.
JD176371 - Sequence 157395 from Patent EP1572962.
JD333726 - Sequence 314750 from Patent EP1572962.
JD183801 - Sequence 164825 from Patent EP1572962.
JD091958 - Sequence 72982 from Patent EP1572962.
JD292257 - Sequence 273281 from Patent EP1572962.
JD268786 - Sequence 249810 from Patent EP1572962.
JD185015 - Sequence 166039 from Patent EP1572962.
JD094710 - Sequence 75734 from Patent EP1572962.
JD039782 - Sequence 20806 from Patent EP1572962.
JD316240 - Sequence 297264 from Patent EP1572962.
JD517890 - Sequence 498914 from Patent EP1572962.
JD212727 - Sequence 193751 from Patent EP1572962.
JD198116 - Sequence 179140 from Patent EP1572962.
JD413416 - Sequence 394440 from Patent EP1572962.
JD246971 - Sequence 227995 from Patent EP1572962.
JD135927 - Sequence 116951 from Patent EP1572962.
JD361934 - Sequence 342958 from Patent EP1572962.
JD453665 - Sequence 434689 from Patent EP1572962.
JD117148 - Sequence 98172 from Patent EP1572962.
JD482690 - Sequence 463714 from Patent EP1572962.
JD233051 - Sequence 214075 from Patent EP1572962.
JD282213 - Sequence 263237 from Patent EP1572962.
JD332868 - Sequence 313892 from Patent EP1572962.
JD449449 - Sequence 430473 from Patent EP1572962.
JD538007 - Sequence 519031 from Patent EP1572962.
JD136233 - Sequence 117257 from Patent EP1572962.
JD136234 - Sequence 117258 from Patent EP1572962.
JD243264 - Sequence 224288 from Patent EP1572962.
JD079658 - Sequence 60682 from Patent EP1572962.
JD266519 - Sequence 247543 from Patent EP1572962.
JD565709 - Sequence 546733 from Patent EP1572962.
JD278059 - Sequence 259083 from Patent EP1572962.
JD216611 - Sequence 197635 from Patent EP1572962.
JD210390 - Sequence 191414 from Patent EP1572962.
JD191288 - Sequence 172312 from Patent EP1572962.
JD390004 - Sequence 371028 from Patent EP1572962.
JD199281 - Sequence 180305 from Patent EP1572962.
JD561455 - Sequence 542479 from Patent EP1572962.
JD282026 - Sequence 263050 from Patent EP1572962.
JD281155 - Sequence 262179 from Patent EP1572962.
JD401947 - Sequence 382971 from Patent EP1572962.
JD421676 - Sequence 402700 from Patent EP1572962.
JD446319 - Sequence 427343 from Patent EP1572962.
JD359901 - Sequence 340925 from Patent EP1572962.
JD090404 - Sequence 71428 from Patent EP1572962.
JD131011 - Sequence 112035 from Patent EP1572962.
JD281869 - Sequence 262893 from Patent EP1572962.
JD268944 - Sequence 249968 from Patent EP1572962.
JD454700 - Sequence 435724 from Patent EP1572962.
JD376282 - Sequence 357306 from Patent EP1572962.
JD086572 - Sequence 67596 from Patent EP1572962.
JD255470 - Sequence 236494 from Patent EP1572962.
JD096309 - Sequence 77333 from Patent EP1572962.
JD044137 - Sequence 25161 from Patent EP1572962.
JD331739 - Sequence 312763 from Patent EP1572962.
JD182467 - Sequence 163491 from Patent EP1572962.
JD350930 - Sequence 331954 from Patent EP1572962.
JD512480 - Sequence 493504 from Patent EP1572962.
JD097399 - Sequence 78423 from Patent EP1572962.
JD050799 - Sequence 31823 from Patent EP1572962.
JD518755 - Sequence 499779 from Patent EP1572962.
JD487474 - Sequence 468498 from Patent EP1572962.
JD493661 - Sequence 474685 from Patent EP1572962.
JD401852 - Sequence 382876 from Patent EP1572962.
JD422063 - Sequence 403087 from Patent EP1572962.
JD266570 - Sequence 247594 from Patent EP1572962.
JD444380 - Sequence 425404 from Patent EP1572962.
JD369142 - Sequence 350166 from Patent EP1572962.
JD487474 - Sequence 468498 from Patent EP1572962.
JD084428 - Sequence 65452 from Patent EP1572962.
JD247825 - Sequence 228849 from Patent EP1572962.
JD101562 - Sequence 82586 from Patent EP1572962.
JD326945 - Sequence 307969 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_018304, NP_060774, PRR11_HUMAN, Q96HE9, Q9NUZ7, Q9NXE9
UCSC ID: uc002ixf.2
RefSeq Accession: NM_018304
Protein: Q96HE9 (aka PRR11_HUMAN)
CCDS: CCDS11614.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_018304.3
exon count: 10CDS single in 3' UTR: no RNA size: 6487
ORF size: 1083CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2309.00frame shift in genome: no % Coverage: 99.78
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 4966# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.