Human Gene MED20 (uc011dui.3) Description and Page Index
Description: Homo sapiens mediator complex subunit 20 (MED20), mRNA. RefSeq Summary (NM_004275): This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]. Transcript (Including UTRs) Position: hg19 chr6:41,873,092-41,888,877 Size: 15,786 Total Exon Count: 3 Strand: - Coding Region Position: hg19 chr6:41,874,560-41,874,910 Size: 351 Coding Exon Count: 1
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC063509 - Homo sapiens cDNA clone IMAGE:3862384, partial cds. BC012618 - Homo sapiens mediator complex subunit 20, mRNA (cDNA clone MGC:13654 IMAGE:4272961), complete cds. BC033498 - Homo sapiens Trf (TATA binding protein-related factor)-proximal homolog (Drosophila), mRNA (cDNA clone IMAGE:5174972). BC015189 - Homo sapiens Trf (TATA binding protein-related factor)-proximal homolog (Drosophila), mRNA (cDNA clone IMAGE:4077017). AL050196 - Homo sapiens mRNA; cDNA DKFZp586D2223 (from clone DKFZp586D2223). AJ420544 - Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1476271. AF116602 - Homo sapiens PRO0213 mRNA, complete cds. BC032552 - Homo sapiens mediator complex subunit 20, mRNA (cDNA clone MGC:45256 IMAGE:5555309), complete cds. BC019866 - Homo sapiens mediator complex subunit 20, mRNA (cDNA clone MGC:29869 IMAGE:4470496), complete cds. AK097385 - Homo sapiens cDNA FLJ40066 fis, clone TESOP2000510, highly similar to TRF-proximal protein homolog. AK023092 - Homo sapiens cDNA FLJ13030 fis, clone NT2RP3001111, highly similar to Homo sapiens TRF-proximal protein mRNA. JD054813 - Sequence 35837 from Patent EP1572962. JD250311 - Sequence 231335 from Patent EP1572962. JD092275 - Sequence 73299 from Patent EP1572962. JD273434 - Sequence 254458 from Patent EP1572962. JD430748 - Sequence 411772 from Patent EP1572962. JD501197 - Sequence 482221 from Patent EP1572962. JD089173 - Sequence 70197 from Patent EP1572962. JD313817 - Sequence 294841 from Patent EP1572962. JD233881 - Sequence 214905 from Patent EP1572962. JD493041 - Sequence 474065 from Patent EP1572962. JD248398 - Sequence 229422 from Patent EP1572962. AK307070 - Homo sapiens cDNA, FLJ97018. AK300573 - Homo sapiens cDNA FLJ60159 complete cds, highly similar to TRF-proximal protein homolog. BC040950 - Homo sapiens mediator complex subunit 20, mRNA (cDNA clone MGC:48835 IMAGE:6042296), complete cds. JD236842 - Sequence 217866 from Patent EP1572962. JD078374 - Sequence 59398 from Patent EP1572962. JD403131 - Sequence 384155 from Patent EP1572962. AK293412 - Homo sapiens cDNA FLJ53711 complete cds, highly similar to TRF-proximal protein homolog. JD259679 - Sequence 240703 from Patent EP1572962. JD258545 - Sequence 239569 from Patent EP1572962. AF097725 - Homo sapiens TRF-proximal protein mRNA, complete cds. JD156946 - Sequence 137970 from Patent EP1572962. KJ892780 - Synthetic construct Homo sapiens clone ccsbBroadEn_02174 MED20 gene, encodes complete protein. EU446931 - Synthetic construct Homo sapiens clone IMAGE:100070333; IMAGE:100012140; FLH257197.01L mediator complex subunit 20 (MED20) gene, encodes complete protein. AB463862 - Synthetic construct DNA, clone: pF1KB7573, Homo sapiens MED20 gene for mediator complex subunit 20, without stop codon, in Flexi system. JD214388 - Sequence 195412 from Patent EP1572962.