Human Gene TLX1NB (uc001ksv.3) Description and Page Index
  Description: Homo sapiens TLX1 neighbor (TLX1NB), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:102,849,078-102,890,903 Size: 41,826 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg19 chr10:102,849,294-102,849,662 Size: 369 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:102,849,078-102,890,903)mRNA (may differ from genome)Protein (122 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblExonPrimerGeneCardsGeneNetworkHGNCHPRD
LynxMGIneXtProtPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: TLXNB_HUMAN
DESCRIPTION: RecName: Full=Putative TLX1 neighbor protein; AltName: Full=TLX1 divergent gene protein;
MISCELLANEOUS: Oriented in a head-to-head manner with TLX1/HOX11. Both genes share the same promoter with robust bidirectional activity.
CAUTION: Product of a dubious CDS prediction.

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.52 RPKM in Spleen
Total median expression: 2.55 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -487.621297-0.376 Picture PostScript Text
3' UTR -65.60216-0.304 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on P0CAT3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC019674 - Homo sapiens TLX1 divergent, mRNA (cDNA clone IMAGE:4943792), with apparent retained intron.
Y11608 - H.sapiens mRNA fragment APT-B7.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001085398, NP_001078867, P0CAT3, TDI, TLXNB_HUMAN
UCSC ID: uc001ksv.3
RefSeq Accession: NM_001085398
Protein: P0CAT3 (aka TLXNB_HUMAN)
CCDS: CCDS60615.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001085398.1
exon count: 3CDS single in 3' UTR: no RNA size: 1882
ORF size: 369CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 245.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.