Human Gene MIR5188 (uc031qkf.1) Description and Page Index
  Description: Homo sapiens microRNA 5188 (MIR5188), microRNA.
RefSeq Summary (NR_049820): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## Transcript is intronless :: LM611539.1 [ECO:0000345] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: hg19 chr12:125,400,093-125,400,205 Size: 113 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksRNA-Seq ExpressionMicroarray ExpressionOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:125,400,093-125,400,205)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerHGNCLynxPubMedStanford SOURCE

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.80 RPKM in Testis
Total median expression: 3.93 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  LF206964 - JP 2014500723-A/14467: Polycomb-Associated Non-Coding RNAs.
HZ409638 - JP 2015528002-A/2235: CHIRAL CONTROL.
LG052972 - KR 1020150036642-A/2238: CHIRAL CONTROL.
JD025438 - Sequence 6462 from Patent EP1572962.
JD033538 - Sequence 14562 from Patent EP1572962.
JD035077 - Sequence 16101 from Patent EP1572962.
HZ482127 - JP 2015535430-A/2633: TERMINALLY MODIFIED RNA.
HZ792058 - JP 2016504050-A/3803: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC514790 - Sequence 5043 from Patent WO2014113089.
LF161520 - JP 2016513950-A/1586: Oligomers with improved off-target profile.
LQ072378 - Sequence 2702 from Patent EP2964234.
MA645879 - JP 2017113010-A/3803: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733763 - JP 2017140048-A/2633: TERMINALLY MODIFIED RNA.
MA405840 - WO 2018155427-A/614: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MA442541 - JP 2018138019-A/14467: Polycomb-Associated Non-Coding RNAs.
MA802932 - JP 2018183181-A/3803: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_049820
UCSC ID: uc031qkf.1
RefSeq Accession: NR_049820

-  Gene Model Information
 
category: noncoding nonsense-mediated-decay: no RNA accession: NR_049820.1
exon count: 1CDS single in 3' UTR: no RNA size: 113
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 344.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.