Human Gene FAM160B2 (uc011kyx.2) Description and Page Index
  Description: Homo sapiens family with sequence similarity 160, member B2 (FAM160B2), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr8:21,946,714-21,961,891 Size: 15,178 Total Exon Count: 17 Strand: +
Coding Region
   Position: hg19 chr8:21,946,765-21,960,442 Size: 13,678 Coding Exon Count: 17 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr8:21,946,714-21,961,891)mRNA (may differ from genome)Protein (743 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
neXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Protein FAM160B2; AltName: Full=Retinoic acid-induced protein 16;
SIMILARITY: Belongs to the UPF0518 family.
SEQUENCE CAUTION: Sequence=AAH52237.1; Type=Erroneous initiation; Sequence=AAI12148.2; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAI12148.2; Type=Frameshift; Positions=291; Sequence=AAQ06676.1; Type=Frameshift; Positions=258, 727; Sequence=BAB15137.1; Type=Erroneous initiation; Sequence=BAG38002.1; Type=Erroneous initiation; Sequence=BAG51483.1; Type=Erroneous initiation;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 45.53 RPKM in Pituitary
Total median expression: 1170.83 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -26.1051-0.512 Picture PostScript Text
3' UTR -679.761449-0.469 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019384 - RetinoicA-induced_16-like

Pfam Domains:
PF10257 - Retinoic acid induced 16-like protein

ModBase Predicted Comparative 3D Structure on Q86V87
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein Sequence    

-  Descriptions from all associated GenBank mRNAs
  FJ492929 - Homo sapiens clone MF1512 immunoglobulin heavy chain variable region mRNA, partial cds.
AK126408 - Homo sapiens cDNA FLJ44444 fis, clone UTERU2020491.
BC052237 - Homo sapiens family with sequence similarity 160, member B2, mRNA (cDNA clone IMAGE:5428454), partial cds.
AK294646 - Homo sapiens cDNA FLJ55841 complete cds, highly similar to Homo sapiens retinoic acid induced 16 (RAI16), mRNA.
AK001987 - Homo sapiens cDNA FLJ11125 fis, clone PLACE1006195.
JD020891 - Sequence 1915 from Patent EP1572962.
JD022291 - Sequence 3315 from Patent EP1572962.
AF495722 - Homo sapiens FP13191 mRNA, complete cds.
BC112147 - Homo sapiens family with sequence similarity 160, member B2, mRNA (cDNA clone IMAGE:8327615), partial cds.
AK055191 - Homo sapiens cDNA FLJ30629 fis, clone CTONG2002073, highly similar to Homo sapiens retinoic acid induced 16 (RAI16), mRNA.
BC012865 - Homo sapiens family with sequence similarity 160, member B2, mRNA (cDNA clone IMAGE:3882535), partial cds.
JD261714 - Sequence 242738 from Patent EP1572962.
HQ258020 - Synthetic construct Homo sapiens clone IMAGE:100072329 Unknown protein gene, encodes complete protein.
KJ903088 - Synthetic construct Homo sapiens clone ccsbBroadEn_12482 FAM160B2 gene, encodes complete protein.
BC013350 - Homo sapiens family with sequence similarity 160, member B2, mRNA (cDNA clone IMAGE:3842281), partial cds.
AK025454 - Homo sapiens cDNA: FLJ21801 fis, clone HEP00707.
AK095924 - Homo sapiens cDNA FLJ38605 fis, clone HEART2004931.
AK315634 - Homo sapiens cDNA, FLJ96721, highly similar to Homo sapiens retinoic acid induced 16 (RAI16), mRNA.
AK025411 - Homo sapiens cDNA: FLJ21758 fis, clone COLF6746.
AF318332 - Homo sapiens pp13191 mRNA, complete cds.
JD546943 - Sequence 527967 from Patent EP1572962.
JD185619 - Sequence 166643 from Patent EP1572962.
JD324992 - Sequence 306016 from Patent EP1572962.
JD423610 - Sequence 404634 from Patent EP1572962.
JD483554 - Sequence 464578 from Patent EP1572962.
JD079022 - Sequence 60046 from Patent EP1572962.
JD379293 - Sequence 360317 from Patent EP1572962.
JD540779 - Sequence 521803 from Patent EP1572962.
JD201826 - Sequence 182850 from Patent EP1572962.
JD384162 - Sequence 365186 from Patent EP1572962.
JD208924 - Sequence 189948 from Patent EP1572962.
JD495564 - Sequence 476588 from Patent EP1572962.
JD278907 - Sequence 259931 from Patent EP1572962.
JD543475 - Sequence 524499 from Patent EP1572962.
JD492629 - Sequence 473653 from Patent EP1572962.
JD184643 - Sequence 165667 from Patent EP1572962.
JD037341 - Sequence 18365 from Patent EP1572962.
JD500340 - Sequence 481364 from Patent EP1572962.
JD373326 - Sequence 354350 from Patent EP1572962.
JD340360 - Sequence 321384 from Patent EP1572962.
JD336829 - Sequence 317853 from Patent EP1572962.
JD117811 - Sequence 98835 from Patent EP1572962.
JD453550 - Sequence 434574 from Patent EP1572962.
JD394133 - Sequence 375157 from Patent EP1572962.
JD200553 - Sequence 181577 from Patent EP1572962.
JD504623 - Sequence 485647 from Patent EP1572962.
JD051906 - Sequence 32930 from Patent EP1572962.
JD482813 - Sequence 463837 from Patent EP1572962.
JD205548 - Sequence 186572 from Patent EP1572962.
JD070816 - Sequence 51840 from Patent EP1572962.
JD141088 - Sequence 122112 from Patent EP1572962.
JD404297 - Sequence 385321 from Patent EP1572962.
JD434296 - Sequence 415320 from Patent EP1572962.
JD037316 - Sequence 18340 from Patent EP1572962.
JD080803 - Sequence 61827 from Patent EP1572962.
JD264755 - Sequence 245779 from Patent EP1572962.
JD295093 - Sequence 276117 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RDQ5, B3KNX1, F16B2_HUMAN, FP13191, NM_022749, NP_073586, Q2M211, Q71JB5, Q7L3J6, Q86V87, Q969T0, Q9H6W4, RAI16
UCSC ID: uc011kyx.2
RefSeq Accession: NM_022749
Protein: Q86V87 (aka F16B2_HUMAN)
CCDS: CCDS6021.2

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_022749.5
exon count: 17CDS single in 3' UTR: no RNA size: 3759
ORF size: 2232CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 4448.00frame shift in genome: no % Coverage: 99.28
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 1195# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.