Human Gene BEX4 (uc004ejw.4) Description and Page Index
Description: Homo sapiens brain expressed, X-linked 4 (BEX4), transcript variant 1, mRNA. RefSeq Summary (NM_001127688): This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]. Transcript (Including UTRs) Position: hg19 chrX:102,470,020-102,472,128 Size: 2,109 Total Exon Count: 2 Strand: + Coding Region Position: hg19 chrX:102,471,082-102,471,444 Size: 363 Coding Exon Count: 1
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF04538 - Brain expressed X-linked like family
ModBase Predicted Comparative 3D Structure on Q9NWD9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.