Human Gene MIR4523 (uc021tty.1) Description and Page Index
  Description: Homo sapiens microRNA 4523 (MIR4523), microRNA.
RefSeq Summary (NR_039749): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Transcript (Including UTRs)
   Position: hg19 chr17:27,717,680-27,717,748 Size: 69 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksMicroarray ExpressionOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:27,717,680-27,717,748)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerHGNCLynxPubMedStanford SOURCE

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  HZ409412 - JP 2015528002-A/2009: CHIRAL CONTROL.
LG052746 - KR 1020150036642-A/2012: CHIRAL CONTROL.
HZ083215 - JP 2015513906-A/572: Stem Cell Microparticles.
HZ436996 - JP 2015529450-A/572: Stem Cell Microparticles.
HZ481704 - JP 2015535430-A/2210: TERMINALLY MODIFIED RNA.
HZ791635 - JP 2016504050-A/3380: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC172200 - Sequence 572 from Patent WO2013150303.
JC514367 - Sequence 4620 from Patent WO2014113089.
JC573011 - Sequence 572 from Patent WO2014125276.
JC582699 - Sequence 572 from Patent WO2014125277.
JE954395 - Sequence 572 from Patent WO2015052526.
JE956148 - Sequence 572 from Patent WO2015052527.
LF137900 - JP 2016507550-A/572: Method of Producing Microparticles.
LF160924 - JP 2016513950-A/990: Oligomers with improved off-target profile.
LF162865 - JP 2016513095-A/572: Stem Cell Microparticles and miRNA.
LF953617 - JP 2016534103-A/572: Stem Cell Microparticles and miRNA.
LG005962 - KR 1020150004822-A/572: STEM CELL MICROPARTICLES.
LG053658 - KR 1020150059168-A/572: STEM CELL MICROPARTICLES.
LG240897 - KR 1020160035087-A/572: STEM CELL MICROPARTICLES AND MIRNA.
LQ071955 - Sequence 2279 from Patent EP2964234.
LV470982 - JP 2016534036-A/572: Stem Cell Microparticles and miRNA.
MA645456 - JP 2017113010-A/3380: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733340 - JP 2017140048-A/2210: TERMINALLY MODIFIED RNA.
MA405452 - WO 2018155427-A/226: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MP015022 - Sequence 225 from Patent WO2019016252.
MA802509 - JP 2018183181-A/3380: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MP129672 - Sequence 572 from Patent EP3470073.
MP162595 - Sequence 572 from Patent WO2019069093.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_039749
UCSC ID: uc021tty.1
RefSeq Accession: NR_039749

-  Gene Model Information
 
category: noncoding nonsense-mediated-decay: no RNA accession: NR_039749.1
exon count: 1CDS single in 3' UTR: no RNA size: 69
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 0.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.