ID:SPS2L_HUMAN DESCRIPTION: RecName: Full=SPATS2-like protein; AltName: Full=DNA polymerase-transactivated protein 6; AltName: Full=Stress granule and nucleolar protein; Short=SGNP; SUBCELLULAR LOCATION: Cytoplasm. Nucleus, nucleolus. Note=During oxidative stress as well as UV irradiation, energy deprivation or heat shock, relocalizes to cytoplasmic stress granules. In the nucleus, found in structures lacking NPM1. SIMILARITY: Belongs to the SPATS2 family. SEQUENCE CAUTION: Sequence=AAG22487.1; Type=Frameshift; Positions=92;
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): SPATS2L CDC HuGE Published Literature: SPATS2L Positive Disease Associations: Creatinine Related Studies:
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF07139 - Protein of unknown function (DUF1387)
ModBase Predicted Comparative 3D Structure on Q9NUQ6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.