Human Gene CEP44 (uc010iro.2) Description and Page Index
  Description: Homo sapiens centrosomal protein 44kDa (CEP44), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr4:175,205,055-175,254,531 Size: 49,477 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chr4:175,220,273-175,252,746 Size: 32,474 Coding Exon Count: 9 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:175,205,055-175,254,531)mRNA (may differ from genome)Protein (399 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
H-INVHGNCHPRDLynxMGIPubMed
Stanford SOURCEUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.36 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 159.45 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -107.40305-0.352 Picture PostScript Text
3' UTR -435.101785-0.244 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15007 - Centrosomal spindle body, CEP44

ModBase Predicted Comparative 3D Structure on Q9C0F1-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Descriptions from all associated GenBank mRNAs
  BC038667 - Homo sapiens KIAA1712, mRNA (cDNA clone MGC:33587 IMAGE:4823994), complete cds.
AK292484 - Homo sapiens cDNA FLJ78628 complete cds.
AK094961 - Homo sapiens cDNA FLJ37642 fis, clone BRHIP2000163.
KJ904892 - Synthetic construct Homo sapiens clone ccsbBroadEn_14286 CEP44 gene, encodes complete protein.
JD064781 - Sequence 45805 from Patent EP1572962.
JD415582 - Sequence 396606 from Patent EP1572962.
AB051499 - Homo sapiens KIAA1712 mRNA for KIAA1712 protein.
JD489875 - Sequence 470899 from Patent EP1572962.
JD305766 - Sequence 286790 from Patent EP1572962.
AB384268 - Synthetic construct DNA, clone: pF1KSDA1712, Homo sapiens KIAA1712 gene for KIAA1712 protein, complete cds, without stop codon, in Flexi system.
AY426674 - Homo sapiens HBV PreS1-transactivated protein 3 mRNA, complete cds.
JD411358 - Sequence 392382 from Patent EP1572962.
JD167468 - Sequence 148492 from Patent EP1572962.
JD194093 - Sequence 175117 from Patent EP1572962.
JD305299 - Sequence 286323 from Patent EP1572962.
JD096355 - Sequence 77379 from Patent EP1572962.
JD345437 - Sequence 326461 from Patent EP1572962.
JD309200 - Sequence 290224 from Patent EP1572962.
JD097326 - Sequence 78350 from Patent EP1572962.
JD052115 - Sequence 33139 from Patent EP1572962.
JD349142 - Sequence 330166 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: KIAA1712, NM_001145314, NP_001138786, Q9C0F1-2
UCSC ID: uc010iro.2
RefSeq Accession: NM_001145314
Protein: Q9C0F1-2, splice isoform of Q9C0F1 CCDS: CCDS47163.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001145314.1
exon count: 11CDS single in 3' UTR: no RNA size: 3290
ORF size: 1200CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2562.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.