Human Gene MYNN (uc010hwo.3) Description and Page Index
Description: Homo sapiens myoneurin (MYNN), transcript variant 3, mRNA. RefSeq Summary (NM_001185119): This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 14. [provided by RefSeq, Jun 2010]. Transcript (Including UTRs) Position: hg19 chr3:169,492,053-169,507,504 Size: 15,452 Total Exon Count: 6 Strand: + Coding Region Position: hg19 chr3:169,492,084-169,504,466 Size: 12,383 Coding Exon Count: 6
Celiac Disease Patrick C A Dubois et al. Nature genetics 2010, Multiple common variants for celiac disease influencing immune gene expression., Nature genetics.
Colorectal Neoplasms Richard S Houlston et al. Nature genetics 2010, Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33., Nature genetics.
Multiple Sclerosis Stephen Sawcer et al. Nature 2011, Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis., Nature.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NPC7-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.