Human Gene ANKRD16 (uc010qat.2) Description and Page Index
  Description: Homo sapiens ankyrin repeat domain 16 (ANKRD16), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:5,903,689-5,931,860 Size: 28,172 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg19 chr10:5,920,093-5,931,317 Size: 11,225 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr10:5,903,689-5,931,860)mRNA (may differ from genome)Protein (361 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
OMIMPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Ankyrin repeat domain-containing protein 16;
SIMILARITY: Contains 9 ANK repeats.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 10.12 RPKM in Testis
Total median expression: 198.67 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -299.90543-0.552 Picture PostScript Text
3' UTR -345.60999-0.346 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom

Pfam Domains:
PF00023 - Ankyrin repeat
PF12796 - Ankyrin repeats (3 copies)
PF13606 - Ankyrin repeat
PF13637 - Ankyrin repeats (many copies)
PF13857 - Ankyrin repeats (many copies)

SCOP Domains:
48403 - Ankyrin repeat

ModBase Predicted Comparative 3D Structure on Q6P6B7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein Sequence    

-  Descriptions from all associated GenBank mRNAs
  KJ894036 - Synthetic construct Homo sapiens clone ccsbBroadEn_03430 ANKRD16 gene, encodes complete protein.
HQ447657 - Synthetic construct Homo sapiens clone IMAGE:100071003; CCSB013769_01 ankyrin repeat domain 16 (ANKRD16) gene, encodes complete protein.
BC067892 - Homo sapiens ankyrin repeat domain 16, mRNA (cDNA clone IMAGE:5275012), with apparent retained intron.
AL137614 - Homo sapiens mRNA; cDNA DKFZp434N1511 (from clone DKFZp434N1511); partial cds.
BC017324 - Homo sapiens ankyrin repeat domain 16, mRNA (cDNA clone IMAGE:4551222), with apparent retained intron.
AK093489 - Homo sapiens cDNA FLJ36170 fis, clone TESTI2026196.
JD421491 - Sequence 402515 from Patent EP1572962.
JD135197 - Sequence 116221 from Patent EP1572962.
AK094497 - Homo sapiens cDNA FLJ37178 fis, clone BRACE2028741.
AK129672 - Homo sapiens cDNA FLJ26161 fis, clone ADG02602.
BC062346 - Homo sapiens ankyrin repeat domain 16, mRNA (cDNA clone MGC:71345 IMAGE:3845142), complete cds.
CU687540 - Synthetic construct Homo sapiens gateway clone IMAGE:100022397 5' read ANKRD16 mRNA.
JD226597 - Sequence 207621 from Patent EP1572962.
JD325318 - Sequence 306342 from Patent EP1572962.
JD100600 - Sequence 81624 from Patent EP1572962.
JD396775 - Sequence 377799 from Patent EP1572962.
JD152072 - Sequence 133096 from Patent EP1572962.
JD085965 - Sequence 66989 from Patent EP1572962.
JD408446 - Sequence 389470 from Patent EP1572962.
JD416405 - Sequence 397429 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A6NEF0, ANR16_HUMAN, NM_019046, NP_061919, Q6P6B7, Q9NT01
UCSC ID: uc010qat.2
RefSeq Accession: NM_019046
Protein: Q6P6B7 (aka ANR16_HUMAN)
CCDS: CCDS31136.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_019046.2
exon count: 8CDS single in 3' UTR: no RNA size: 2646
ORF size: 1086CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1444.00frame shift in genome: no % Coverage: 99.32
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.