Human Gene YAE1D1 (uc003thc.4) Description and Page Index
  Description: Homo sapiens Yae1 domain containing 1 (YAE1D1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr7:39,606,003-39,612,480 Size: 6,478 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg19 chr7:39,606,018-39,612,305 Size: 6,288 Coding Exon Count: 3 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr7:39,606,003-39,612,480)mRNA (may differ from genome)Protein (226 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
neXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.05 RPKM in Testis
Total median expression: 215.90 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -21.20175-0.121 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019191 - Essential_protein_Yae1_N

Pfam Domains:
PF09811 - Essential protein Yae1, N terminal

ModBase Predicted Comparative 3D Structure on Q9NRH1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologGenome Browser
Gene Details    Gene Details
Gene Sorter    Gene Sorter
  Ensembl  SGD
  Protein Sequence  Protein Sequence
  Alignment  Alignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0006413 translational initiation
GO:0042273 ribosomal large subunit biogenesis

-  Descriptions from all associated GenBank mRNAs
  LP896449 - Sequence 1313 from Patent EP3253886.
AK314937 - Homo sapiens cDNA, FLJ95848.
AK293511 - Homo sapiens cDNA FLJ57706 complete cds.
BC022043 - Homo sapiens chromosome 7 open reading frame 36, mRNA (cDNA clone MGC:27139 IMAGE:4734433), complete cds.
AF226046 - Homo sapiens GK003 (GK003) mRNA, complete cds.
DQ896074 - Synthetic construct Homo sapiens clone IMAGE:100010534; FLH263677.01L; RZPDo839E0565D chromosome 7 open reading frame 36 (C7orf36) gene, encodes complete protein.
DQ896075 - Synthetic construct Homo sapiens clone IMAGE:100010535; FLH190089.01L; RZPDo839E0665D chromosome 7 open reading frame 36 (C7orf36) gene, encodes complete protein.
DQ892829 - Synthetic construct clone IMAGE:100005459; FLH190093.01X; RZPDo839E0675D chromosome 7 open reading frame 36 (C7orf36) gene, encodes complete protein.
KJ899288 - Synthetic construct Homo sapiens clone ccsbBroadEn_08682 YAE1D1 gene, encodes complete protein.
CR457198 - Homo sapiens full open reading frame cDNA clone RZPDo834F068D for gene C7orf36, chromosome 7 open reading frame 36; complete cds, incl. stopcodon.
BX648555 - Homo sapiens mRNA; cDNA DKFZp779B0135 (from clone DKFZp779B0135).
JD245657 - Sequence 226681 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A4D1W4, C7orf36, GK003, NM_020192, NP_064577, Q6IAF7, Q8WVZ5, Q9NRH1, YAED1_HUMAN
UCSC ID: uc003thc.4
RefSeq Accession: NM_020192
Protein: Q9NRH1 (aka YAED1_HUMAN)
CCDS: CCDS5459.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_020192.3
exon count: 3CDS single in 3' UTR: no RNA size: 907
ORF size: 681CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1562.00frame shift in genome: no % Coverage: 96.03
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.