Human Gene LOC100133315 (uc021qmt.1) Description and Page Index
  Description: Homo sapiens transient receptor potential cation channel, subfamily C, member 2-like (LOC100133315), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr11:71,576,555-71,639,493 Size: 62,939 Total Exon Count: 7 Strand: -
Coding Region
   Position: hg19 chr11:71,576,883-71,634,399 Size: 57,517 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:71,576,555-71,639,493)mRNA (may differ from genome)Protein (179 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsLynxMGI
PubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: E9PQ18_HUMAN
DESCRIPTION: SubName: Full=Uncharacterized protein;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): LOC100133315
CDC HuGE Published Literature: LOC100133315

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.88 RPKM in Testis
Total median expression: 20.79 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -126.20377-0.335 Picture PostScript Text
3' UTR -55.65328-0.170 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008979 - Galactose-bd-like
IPR002706 - Xrcc1_N

Pfam Domains:
PF01834 - XRCC1 N terminal domain

SCOP Domains:
49785 - Galactose-binding domain-like

ModBase Predicted Comparative 3D Structure on E9PQ18
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
 Gene Details    
 Gene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003684 damaged DNA binding

Biological Process:
GO:0000012 single strand break repair
GO:0006284 base-excision repair

Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  AK131288 - Homo sapiens cDNA FLJ16241 fis, clone HCASM2008536, weakly similar to DNA-REPAIR PROTEIN XRCC1.

-  Other Names for This Gene
  Alternate Gene Symbols: E9PQ18, E9PQ18_HUMAN, NR_029192
UCSC ID: uc021qmt.1
RefSeq Accession: NR_029192
Protein: E9PQ18

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_029192.1
exon count: 7CDS single in 3' UTR: no RNA size: 1262
ORF size: 540CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1071.00frame shift in genome: no % Coverage: 98.65
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.