Human Gene ZNF322 (uc021yny.1) Description and Page Index
Description: Homo sapiens zinc finger protein 322 (ZNF322), transcript variant 3, mRNA. RefSeq Summary (NM_001242798): ZNF322A is a member of the zinc-finger transcription factor family and may regulate transcriptional activation in MAPK (see MAPK1; MIM 176948) signaling pathways (Li et al., 2004 [PubMed 15555580]).[supplied by OMIM, Mar 2008]. Transcript (Including UTRs) Position: hg19 chr6:26,634,611-26,659,980 Size: 25,370 Total Exon Count: 3 Strand: - Coding Region Position: hg19 chr6:26,637,573-26,638,781 Size: 1,209 Coding Exon Count: 1
ID:ZN322_HUMAN DESCRIPTION: RecName: Full=Zinc finger protein 322; AltName: Full=Zinc finger protein 322A; AltName: Full=Zinc finger protein 388; AltName: Full=Zinc finger protein 489; FUNCTION: Involved in transcriptional regulation as an activator. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Ubiquitous. Highly expressed in heart and skeletal muscle. DEVELOPMENTAL STAGE: Expressed in embryo as early as the 11th week of gestation. SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family. SIMILARITY: Contains 11 C2H2-type zinc fingers. SEQUENCE CAUTION: Sequence=BAB15637.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6U7Q0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:1902459 positive regulation of stem cell population maintenance