Human Gene TCEANC (uc010neg.1) Description and Page Index
  Description: Homo sapiens transcription elongation factor A (SII) N-terminal and central domain containing (TCEANC), mRNA.
Transcript (Including UTRs)
   Position: hg19 chrX:13,671,307-13,682,247 Size: 10,941 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chrX:13,677,806-13,681,683 Size: 3,878 Coding Exon Count: 2 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:13,671,307-13,682,247)mRNA (may differ from genome)Protein (381 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIPubMed
Stanford SOURCETreefamUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.55 RPKM in Spleen
Total median expression: 37.39 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -83.13245-0.339 Picture PostScript Text
3' UTR -162.40564-0.288 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF07500 - Transcription factor S-II (TFIIS), central domain
PF08711 - TFIIS helical bundle-like domain

SCOP Domains:
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon

ModBase Predicted Comparative 3D Structure on Q8N8B7-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK291271 - Homo sapiens cDNA FLJ77132 complete cds.
AK315599 - Homo sapiens cDNA, FLJ96679.
AK294465 - Homo sapiens cDNA FLJ56978 complete cds.
BC020095 - Homo sapiens TFIIS central domain-containing protein 1, mRNA (cDNA clone IMAGE:3925366), with apparent retained intron.
AK097032 - Homo sapiens cDNA FLJ39713 fis, clone SMINT2013170, weakly similar to TRANSCRIPTION FACTOR S-II-RELATED PROTEIN 4.
JD515983 - Sequence 497007 from Patent EP1572962.
JD364967 - Sequence 345991 from Patent EP1572962.
JD126287 - Sequence 107311 from Patent EP1572962.
JD552276 - Sequence 533300 from Patent EP1572962.
JD127531 - Sequence 108555 from Patent EP1572962.
JD230987 - Sequence 212011 from Patent EP1572962.
JD076145 - Sequence 57169 from Patent EP1572962.
JD381709 - Sequence 362733 from Patent EP1572962.
JD109659 - Sequence 90683 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_152634, NP_689847, Q8N8B7-2
UCSC ID: uc010neg.1
RefSeq Accession: NM_152634
Protein: Q8N8B7-2, splice isoform of Q8N8B7 CCDS: CCDS48081.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_152634.2
exon count: 4CDS single in 3' UTR: no RNA size: 1955
ORF size: 1146CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2286.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.