Human Gene MAPK1IP1L (uc001xbq.1) Description and Page Index
  Description: Homo sapiens mitogen-activated protein kinase 1 interacting protein 1-like (MAPK1IP1L), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr14:55,518,362-55,536,912 Size: 18,551 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr14:55,528,402-55,531,345 Size: 2,944 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr14:55,518,362-55,536,912)mRNA (may differ from genome)Protein (245 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
OMIMPubMedStanford SOURCETreefamUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=MAPK-interacting and spindle-stabilizing protein-like; AltName: Full=Mitogen-activated protein kinase 1-interacting protein 1-like;
SIMILARITY: Belongs to the MISS family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 24.57 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 530.62 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -66.90164-0.408 Picture PostScript Text
3' UTR -1507.105567-0.271 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15822 - MAPK-interacting and spindle-stabilising protein-like

ModBase Predicted Comparative 3D Structure on Q8NDC0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

-  Descriptions from all associated GenBank mRNAs
  AK315501 - Homo sapiens cDNA, FLJ96565, Homo sapiens likely ortholog of mouse MAPK-interacting and spindle-stabilizing protein (MISS), mRNA.
AL834285 - Homo sapiens mRNA; cDNA DKFZp566M173 (from clone DKFZp566M173).
AK025580 - Homo sapiens cDNA: FLJ21927 fis, clone HEP04178, highly similar to HSU90909 Human clone 23722 mRNA sequence.
BC015621 - Homo sapiens mitogen-activated protein kinase 1 interacting protein 1-like, mRNA (cDNA clone MGC:23138 IMAGE:4843370), complete cds.
JD467569 - Sequence 448593 from Patent EP1572962.
JD423722 - Sequence 404746 from Patent EP1572962.
AB529091 - Synthetic construct DNA, clone: pF1KB4255, Homo sapiens MAPK1IP1L gene for mitogen-activated protein kinase 1 interacting protein 1-like, without stop codon, in Flexi system.
CU677369 - Synthetic construct Homo sapiens gateway clone IMAGE:100017620 5' read C14orf32 mRNA.
HQ448673 - Synthetic construct Homo sapiens clone IMAGE:100072115; CCSB007591_02 chromosome 14 open reading frame 32 (MAPK1IP1L) gene, encodes complete protein.
KJ899964 - Synthetic construct Homo sapiens clone ccsbBroadEn_09358 MAPK1IP1L gene, encodes complete protein.
JD449332 - Sequence 430356 from Patent EP1572962.
JD392675 - Sequence 373699 from Patent EP1572962.
JD124453 - Sequence 105477 from Patent EP1572962.
JD094300 - Sequence 75324 from Patent EP1572962.
JD537567 - Sequence 518591 from Patent EP1572962.
JD239275 - Sequence 220299 from Patent EP1572962.
JD052581 - Sequence 33605 from Patent EP1572962.
U90909 - Human clone 23722 mRNA sequence.
JD292486 - Sequence 273510 from Patent EP1572962.
JD232235 - Sequence 213259 from Patent EP1572962.
JD046446 - Sequence 27470 from Patent EP1572962.
JD296796 - Sequence 277820 from Patent EP1572962.
JD429931 - Sequence 410955 from Patent EP1572962.
JD313110 - Sequence 294134 from Patent EP1572962.
JD449429 - Sequence 430453 from Patent EP1572962.
JD083502 - Sequence 64526 from Patent EP1572962.
JD251966 - Sequence 232990 from Patent EP1572962.
JD123512 - Sequence 104536 from Patent EP1572962.
JD050273 - Sequence 31297 from Patent EP1572962.
JD426900 - Sequence 407924 from Patent EP1572962.
JD257942 - Sequence 238966 from Patent EP1572962.
JD553202 - Sequence 534226 from Patent EP1572962.
JD198496 - Sequence 179520 from Patent EP1572962.
JD272083 - Sequence 253107 from Patent EP1572962.
JD153330 - Sequence 134354 from Patent EP1572962.
JD161677 - Sequence 142701 from Patent EP1572962.
JD547691 - Sequence 528715 from Patent EP1572962.
JD547692 - Sequence 528716 from Patent EP1572962.
JD407630 - Sequence 388654 from Patent EP1572962.
JD213240 - Sequence 194264 from Patent EP1572962.
JD059631 - Sequence 40655 from Patent EP1572962.
AK054650 - Homo sapiens cDNA FLJ30088 fis, clone BNGH41000010.
JD449710 - Sequence 430734 from Patent EP1572962.
JD431649 - Sequence 412673 from Patent EP1572962.
JD087163 - Sequence 68187 from Patent EP1572962.
JD262175 - Sequence 243199 from Patent EP1572962.
JD165320 - Sequence 146344 from Patent EP1572962.
JD095318 - Sequence 76342 from Patent EP1572962.
JD345432 - Sequence 326456 from Patent EP1572962.
JD345431 - Sequence 326455 from Patent EP1572962.
JD441713 - Sequence 422737 from Patent EP1572962.
JD441714 - Sequence 422738 from Patent EP1572962.
JD441716 - Sequence 422740 from Patent EP1572962.
JD441717 - Sequence 422741 from Patent EP1572962.
JD441718 - Sequence 422742 from Patent EP1572962.
JD241108 - Sequence 222132 from Patent EP1572962.
JD516102 - Sequence 497126 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RDD8, C14orf32, MISSL_HUMAN, NM_144578, NP_653179, Q8NDC0, Q96BG5
UCSC ID: uc001xbq.1
RefSeq Accession: NM_144578
Protein: Q8NDC0 (aka MISSL_HUMAN)
CCDS: CCDS32085.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_144578.3
exon count: 4CDS single in 3' UTR: no RNA size: 6469
ORF size: 738CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1676.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.