Human Gene ZC3H12B (uc010nko.3) Description and Page Index
Description: Homo sapiens zinc finger CCCH-type containing 12B (ZC3H12B), mRNA. RefSeq Summary (NM_001010888): The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease. [provided by RefSeq, May 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC140767.1, SRR1803616.1654.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## Transcript (Including UTRs) Position: hg19 chrX:64,708,615-64,727,767 Size: 19,153 Total Exon Count: 5 Strand: + Coding Region Position: hg19 chrX:64,708,682-64,723,089 Size: 14,408 Coding Exon Count: 5
ID:E9PAJ6_HUMAN DESCRIPTION: SubName: Full=Probable ribonuclease ZC3H12B; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E9PAJ6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.