Human Gene EMC1 (uc001bbo.4) Description and Page Index
Description: Homo sapiens ER membrane protein complex subunit 1 (EMC1), transcript variant 1, mRNA. RefSeq Summary (NM_015047): This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2012]. Transcript (Including UTRs) Position: hg19 chr1:19,542,158-19,578,053 Size: 35,896 Total Exon Count: 23 Strand: - Coding Region Position: hg19 chr1:19,545,797-19,578,003 Size: 32,207 Coding Exon Count: 23
ID:EMC1_HUMAN DESCRIPTION: RecName: Full=ER membrane protein complex subunit 1; Flags: Precursor; SUBUNIT: Component of the ER membrane protein complex (EMC). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: Belongs to the EMC1 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N766
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0034975 protein folding in endoplasmic reticulum