Human Gene PRR23B (uc003esy.1)
  Description: Homo sapiens proline rich 23B (PRR23B), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr3:138,737,873-138,739,768 Size: 1,896 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr3:138,738,706-138,739,503 Size: 798 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:138,737,873-138,739,768)mRNA (may differ from genome)Protein (265 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkHGNCHPRDLynxMGIneXtProt
PubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: PR23B_HUMAN
DESCRIPTION: RecName: Full=Proline-rich protein 23B;
SIMILARITY: Belongs to the PRR23 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.49 RPKM in Testis
Total median expression: 1.49 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -94.20265-0.355 Picture PostScript Text
3' UTR -191.46833-0.230 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018903 - UPF0572

Pfam Domains:
PF10630 - Protein of unknown function (DUF2476)

ModBase Predicted Comparative 3D Structure on Q6ZRT6
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ896206 - Synthetic construct Homo sapiens clone ccsbBroadEn_05600 PRR23B gene, encodes complete protein.
AK127998 - Homo sapiens cDNA FLJ46116 fis, clone TESTI2037209.
BC137146 - Homo sapiens hypothetical gene supported by AK127998, mRNA (cDNA clone MGC:168766 IMAGE:9021143), complete cds.
BC137145 - Homo sapiens hypothetical gene supported by AK127998, mRNA (cDNA clone MGC:168765 IMAGE:9021142), complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RNV9, NM_001013650, NP_001013672, PR23B_HUMAN, Q6ZRT6
UCSC ID: uc003esy.1
RefSeq Accession: NM_001013650
Protein: Q6ZRT6 (aka PR23B_HUMAN)
CCDS: CCDS33868.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001013650.2
exon count: 1CDS single in 3' UTR: no RNA size: 1896
ORF size: 798CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1787.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.