Human Gene NAXD (uc001vrc.3)
Description: Homo sapiens carbohydrate kinase domain containing (NAXD), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr13:111,267,931-111,292,342 Size: 24,412 Total Exon Count: 10 Strand: +
Coding Region
Position: hg19 chr13:111,268,022-111,290,868 Size: 22,847 Coding Exon Count: 10
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF01256 - Carbohydrate kinase
SCOP Domains: 53613 - Ribokinase-like
ModBase Predicted Comparative 3D Structure on Q8IW45-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
AK298917 - Homo sapiens cDNA FLJ55241 complete cds.AK093771 - Homo sapiens cDNA FLJ36452 fis, clone THYMU2013916.AX748297 - Sequence 1822 from Patent EP1308459.AK302117 - Homo sapiens cDNA FLJ55262 complete cds.AK296758 - Homo sapiens cDNA FLJ61130 complete cds.AK057767 - Homo sapiens cDNA FLJ25038 fis, clone CBL03089.AK296227 - Homo sapiens cDNA FLJ52550 complete cds.BC000577 - Homo sapiens hypothetical protein FLJ10769, mRNA (cDNA clone IMAGE:3162721), **** WARNING: chimeric clone ****.AK024260 - Homo sapiens cDNA FLJ14198 fis, clone NT2RP3002512.BC041028 - Homo sapiens carbohydrate kinase domain containing, mRNA (cDNA clone MGC:52265 IMAGE:4098260), complete cds.AK001631 - Homo sapiens cDNA FLJ10769 fis, clone NT2RP4000151.AK225129 - Homo sapiens mRNA for FLJ10769 protein variant, clone: CBL04383.KJ902870 - Synthetic construct Homo sapiens clone ccsbBroadEn_12264 CARKD gene, encodes complete protein.AF091088 - Homo sapiens clone 664 unknown mRNA, partial sequence.AK058043 - Homo sapiens cDNA FLJ25314 fis, clone SYN01173.AK091867 - Homo sapiens cDNA FLJ34548 fis, clone HLUNG2009225.AY203948 - Homo sapiens LP3298 mRNA, complete cds.JD303975 - Sequence 284999 from Patent EP1572962.JD142522 - Sequence 123546 from Patent EP1572962.JD478178 - Sequence 459202 from Patent EP1572962.JD164447 - Sequence 145471 from Patent EP1572962.JD142088 - Sequence 123112 from Patent EP1572962.JD232660 - Sequence 213684 from Patent EP1572962.JD137908 - Sequence 118932 from Patent EP1572962.BC005150 - Homo sapiens hypothetical protein FLJ10769, mRNA (cDNA clone IMAGE:3507998), partial cds.JD465605 - Sequence 446629 from Patent EP1572962.AF151071 - Homo sapiens HSPC237 mRNA, complete cds.JD088038 - Sequence 69062 from Patent EP1572962.JD404212 - Sequence 385236 from Patent EP1572962.DQ588336 - Homo sapiens piRNA piR-55448, complete sequence.JD484026 - Sequence 465050 from Patent EP1572962.JD470907 - Sequence 451931 from Patent EP1572962.BC006416 - Homo sapiens cDNA clone IMAGE:3628583.JD483049 - Sequence 464073 from Patent EP1572962.JD339409 - Sequence 320433 from Patent EP1572962.JD291562 - Sequence 272586 from Patent EP1572962.JD533171 - Sequence 514195 from Patent EP1572962.JD426853 - Sequence 407877 from Patent EP1572962.JD490924 - Sequence 471948 from Patent EP1572962.JD236552 - Sequence 217576 from Patent EP1572962.JD297075 - Sequence 278099 from Patent EP1572962.JD252825 - Sequence 233849 from Patent EP1572962.JD528497 - Sequence 509521 from Patent EP1572962.JD506671 - Sequence 487695 from Patent EP1572962.JD343706 - Sequence 324730 from Patent EP1572962.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: CARKD, NM_018210, NP_060680, Q8IW45-2UCSC ID: uc001vrc.3RefSeq Accession: NM_018210
Protein: Q8IW45-2 , splice isoform of Q8IW45
CCDS: CCDS9513.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_018210.3
exon count:
10 CDS single in 3' UTR:
no
RNA size:
2756
ORF size:
1173 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2430.00 frame shift in genome:
no
% Coverage:
99.35
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.