Human Gene LENG8 (uc002qfw.2) Description and Page Index
  Description: Homo sapiens leukocyte receptor cluster (LRC) member 8 (LENG8), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:54,960,065-54,973,196 Size: 13,132 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg19 chr19:54,962,522-54,972,108 Size: 9,587 Coding Exon Count: 15 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:54,960,065-54,973,196)mRNA (may differ from genome)Protein (800 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
OMIMPubMedStanford SOURCETreefamUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 139.43 RPKM in Ovary
Total median expression: 3790.92 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -187.80479-0.392 Picture PostScript Text
3' UTR -390.251088-0.359 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF03399 - SAC3/GANP family

ModBase Predicted Comparative 3D Structure on Q96PV6-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserGenome BrowserGenome BrowserNo ortholog
Gene DetailsGene Details Gene DetailsGene Details 
Gene SorterGene Sorter Gene SorterGene Sorter 
 Protein SequenceProtein SequenceProtein SequenceProtein Sequence 

-  Descriptions from all associated GenBank mRNAs
  LF207480 - JP 2014500723-A/14983: Polycomb-Associated Non-Coding RNAs.
LF207481 - JP 2014500723-A/14984: Polycomb-Associated Non-Coding RNAs.
AL834532 - Homo sapiens mRNA; cDNA DKFZp434N0612 (from clone DKFZp434N0612).
BC028048 - Homo sapiens leukocyte receptor cluster (LRC) member 8, mRNA (cDNA clone MGC:40108 IMAGE:3907442), complete cds.
AB067519 - Homo sapiens mRNA for KIAA1932 protein, partial cds.
JD559392 - Sequence 540416 from Patent EP1572962.
DQ892704 - Synthetic construct clone IMAGE:100005334; FLH196272.01X; RZPDo839G10154D leukocyte receptor cluster (LRC) member 8 (LENG8) gene, encodes complete protein.
DQ894253 - Synthetic construct Homo sapiens clone IMAGE:100008713; FLH169058.01L; RZPDo839G0193D leukocyte receptor cluster (LRC) member 8 (LENG8) gene, encodes complete protein.
DQ895948 - Synthetic construct Homo sapiens clone IMAGE:100010408; FLH196268.01L; RZPDo839G10153D leukocyte receptor cluster (LRC) member 8 (LENG8) gene, encodes complete protein.
EU176249 - Synthetic construct Homo sapiens clone IMAGE:100006598; FLH263982.01X; RZPDo839G04245D leukocyte receptor cluster (LRC) member 8 (LENG8) gene, encodes complete protein.
AB384326 - Synthetic construct DNA, clone: pF1KSDA1932, Homo sapiens LENG8 gene for leukocyte receptor cluster member 8, complete cds, without stop codon, in Flexi system.
JD462466 - Sequence 443490 from Patent EP1572962.
JD131793 - Sequence 112817 from Patent EP1572962.
AL833879 - Homo sapiens mRNA; cDNA DKFZp434H1015 (from clone DKFZp434H1015).
JD414312 - Sequence 395336 from Patent EP1572962.
AF211974 - Homo sapiens LENG8 mRNA, variant B, partial sequence.
AF211975 - Homo sapiens LENG8 mRNA, variant C, partial sequence.
AF318338 - Homo sapiens pp13842 mRNA, complete cds.
JD149608 - Sequence 130632 from Patent EP1572962.
JD482496 - Sequence 463520 from Patent EP1572962.
AF211973 - Homo sapiens LENG8 mRNA, variant A, partial sequence.
JD341598 - Sequence 322622 from Patent EP1572962.
X58237 - Human mRNA for anti-lectin antibody epitope (clone p36/8-6).
JD398313 - Sequence 379337 from Patent EP1572962.
JD150072 - Sequence 131096 from Patent EP1572962.
JD234969 - Sequence 215993 from Patent EP1572962.
JD297695 - Sequence 278719 from Patent EP1572962.
JD100999 - Sequence 82023 from Patent EP1572962.
JD433301 - Sequence 414325 from Patent EP1572962.
JD263203 - Sequence 244227 from Patent EP1572962.
JD555550 - Sequence 536574 from Patent EP1572962.
JD150630 - Sequence 131654 from Patent EP1572962.
JD419440 - Sequence 400464 from Patent EP1572962.
JD460217 - Sequence 441241 from Patent EP1572962.
JD402311 - Sequence 383335 from Patent EP1572962.
JD391847 - Sequence 372871 from Patent EP1572962.
MA443057 - JP 2018138019-A/14983: Polycomb-Associated Non-Coding RNAs.
MA443058 - JP 2018138019-A/14984: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: KIAA1932, NM_052925, NP_443157, Q96PV6-2
UCSC ID: uc002qfw.2
RefSeq Accession: NM_052925
Protein: Q96PV6-2, splice isoform of Q96PV6 CCDS: CCDS12894.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_052925.2
exon count: 16CDS single in 3' UTR: no RNA size: 3970
ORF size: 2403CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 4543.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.