Human Gene HTATIP2 (uc001mpx.2)
  Description: Homo sapiens HIV-1 Tat interactive protein 2, 30kDa (HTATIP2), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr11:20,385,289-20,405,329 Size: 20,041 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr11:20,385,358-20,404,751 Size: 19,394 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:20,385,289-20,405,329)mRNA (may differ from genome)Protein (276 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMalacards
MGIOMIMPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: HTATIP2
Diseases sorted by gene-association score: hiv-1 (6), hepatocellular carcinoma (4), gnathodiaphyseal dysplasia (3), small cell cancer of the lung, somatic (2), lacrimal gland adenocarcinoma (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 29.49 RPKM in Small Intestine - Terminal Ileum
Total median expression: 593.48 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -24.5069-0.355 Picture PostScript Text
3' UTR -148.68578-0.257 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF13460 - NAD(P)H-binding

SCOP Domains:
51735 - NAD(P)-binding Rossmann-fold domains

ModBase Predicted Comparative 3D Structure on Q9BUP3-3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK292092 - Homo sapiens cDNA FLJ75232 complete cds, highly similar to Homo sapiens HIV-1 Tat interactive protein 2, 30kDa (HTATIP2), mRNA.
BC002439 - Homo sapiens HIV-1 Tat interactive protein 2, 30kDa, mRNA (cDNA clone MGC:1318 IMAGE:3346984), complete cds.
JD476312 - Sequence 457336 from Patent EP1572962.
JD152661 - Sequence 133685 from Patent EP1572962.
JD405942 - Sequence 386966 from Patent EP1572962.
AF092095 - Homo sapiens alternatively spliced product of metastasis-suppressor gene CC3 (TC3) mRNA, complete cds.
U69161 - Homo sapiens CC3 (CC3) mRNA, complete cds.
AK223010 - Homo sapiens mRNA for HIV-1 Tat interactive protein 2, 30kDa variant, clone: HSI15163.
BC015358 - Homo sapiens HIV-1 Tat interactive protein 2, 30kDa, mRNA (cDNA clone MGC:21465 IMAGE:3455757), complete cds.
AK222969 - Homo sapiens mRNA for HIV-1 Tat interactive protein 2, 30kDa variant, clone: HSI01981.
EU446982 - Synthetic construct Homo sapiens clone IMAGE:100069837; IMAGE:100012191; FLH258615.01L HIV-1 Tat interactive protein 2, 30kDa (HTATIP2) gene, encodes complete protein.
AF039103 - Homo sapiens Tat-interacting protein TIP30 mRNA, complete cds.
KJ898239 - Synthetic construct Homo sapiens clone ccsbBroadEn_07633 HTATIP2 gene, encodes complete protein.
AB463744 - Synthetic construct DNA, clone: pF1KB7510, Homo sapiens HTATIP2 gene for HIV-1 Tat interactive protein 2, 30kDa, without stop codon, in Flexi system.
CR456821 - Homo sapiens full open reading frame cDNA clone RZPDo834F0215D for gene HTATIP2, HIV-1 Tat interactive protein 2, 30kDa; complete cds, incl. stopcodon.
JD026504 - Sequence 7528 from Patent EP1572962.
JD027629 - Sequence 8653 from Patent EP1572962.
AK130473 - Homo sapiens cDNA FLJ26963 fis, clone SLV01054.
JD299423 - Sequence 280447 from Patent EP1572962.
JD475580 - Sequence 456604 from Patent EP1572962.
JD268107 - Sequence 249131 from Patent EP1572962.
JD082972 - Sequence 63996 from Patent EP1572962.
JD510819 - Sequence 491843 from Patent EP1572962.
JD315991 - Sequence 297015 from Patent EP1572962.
JD344972 - Sequence 325996 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CC3, NM_001098520, NP_006401, Q9BUP3-3, TIP30
UCSC ID: uc001mpx.2
RefSeq Accession: NM_001098520
Protein: Q9BUP3-3, splice isoform of Q9BUP3 CCDS: CCDS44553.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001098520.1
exon count: 6CDS single in 3' UTR: no RNA size: 1509
ORF size: 831CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1851.00frame shift in genome: no % Coverage: 97.95
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.