Creatinine Shih-Jen Hwang et al. BMC medical genetics 2007, A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study., BMC medical genetics.
[PubMed 17903292]
Kidney function traits and TSH are associated with SNPs on the Affymetrix GeneChip Human Mapping 100K SNP set. These data will serve as a valuable resource for replication as more SNPs associated with kidney function and endocrine traits are identified.
Glomerular Filtration Rate Shih-Jen Hwang et al. BMC medical genetics 2007, A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study., BMC medical genetics.
[PubMed 17903292]
Kidney function traits and TSH are associated with SNPs on the Affymetrix GeneChip Human Mapping 100K SNP set. These data will serve as a valuable resource for replication as more SNPs associated with kidney function and endocrine traits are identified.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5VTB9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK056424 - Homo sapiens cDNA FLJ31862 fis, clone NT2RP7001335. BC034221 - Homo sapiens ring finger protein 220, mRNA (cDNA clone MGC:39525 IMAGE:4814781), complete cds. BC098266 - Homo sapiens ring finger protein 220, mRNA (cDNA clone MGC:120630 IMAGE:40026694), complete cds. BC098300 - Homo sapiens ring finger protein 220, mRNA (cDNA clone MGC:120631 IMAGE:40026695), complete cds. AK025744 - Homo sapiens cDNA: FLJ22091 fis, clone HEP16447, highly similar to AF151080 Homo sapiens HSPC246 mRNA. AK293411 - Homo sapiens cDNA FLJ52472 complete cds. AK297228 - Homo sapiens cDNA FLJ54701 complete cds. JD200367 - Sequence 181391 from Patent EP1572962. JD200351 - Sequence 181375 from Patent EP1572962. JD272536 - Sequence 253560 from Patent EP1572962. JD200352 - Sequence 181376 from Patent EP1572962. JD272537 - Sequence 253561 from Patent EP1572962. JD458522 - Sequence 439546 from Patent EP1572962. AK296038 - Homo sapiens cDNA FLJ54815 complete cds. AK225180 - Homo sapiens mRNA for hypothetical protein LOC55182 variant, clone: CBR05220. AK001459 - Homo sapiens cDNA FLJ10597 fis, clone NT2RP2004802. AK124790 - Homo sapiens cDNA FLJ42800 fis, clone BRAWH3009297. BC073835 - Homo sapiens chromosome 1 open reading frame 164, mRNA (cDNA clone IMAGE:5170310). AK124639 - Homo sapiens cDNA FLJ42648 fis, clone BRACE3027242. JD094687 - Sequence 75711 from Patent EP1572962. JD352226 - Sequence 333250 from Patent EP1572962. JD296283 - Sequence 277307 from Patent EP1572962. BC062600 - Homo sapiens cDNA clone IMAGE:5406896, partial cds. JD370456 - Sequence 351480 from Patent EP1572962. JD335631 - Sequence 316655 from Patent EP1572962. JD495457 - Sequence 476481 from Patent EP1572962. JD280276 - Sequence 261300 from Patent EP1572962. JD318625 - Sequence 299649 from Patent EP1572962. JD253189 - Sequence 234213 from Patent EP1572962. JD280275 - Sequence 261299 from Patent EP1572962. JD224282 - Sequence 205306 from Patent EP1572962. JD174329 - Sequence 155353 from Patent EP1572962. JD480748 - Sequence 461772 from Patent EP1572962. JD210039 - Sequence 191063 from Patent EP1572962. AF151080 - Homo sapiens HSPC246 mRNA, complete cds. JD500243 - Sequence 481267 from Patent EP1572962. JD223192 - Sequence 204216 from Patent EP1572962. JD484476 - Sequence 465500 from Patent EP1572962. JD475164 - Sequence 456188 from Patent EP1572962. JD343327 - Sequence 324351 from Patent EP1572962. BC105790 - Homo sapiens cDNA clone IMAGE:6457164. JD407747 - Sequence 388771 from Patent EP1572962. BC000279 - Homo sapiens ring finger protein 220, mRNA (cDNA clone IMAGE:3357957), complete cds. JD090996 - Sequence 72020 from Patent EP1572962. KJ904794 - Synthetic construct Homo sapiens clone ccsbBroadEn_14188 RNF220 gene, encodes complete protein. JD068414 - Sequence 49438 from Patent EP1572962. JD216020 - Sequence 197044 from Patent EP1572962. JD484358 - Sequence 465382 from Patent EP1572962. JD214987 - Sequence 196011 from Patent EP1572962. JD052633 - Sequence 33657 from Patent EP1572962. JD197217 - Sequence 178241 from Patent EP1572962. JD283473 - Sequence 264497 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q5VTB9 (Reactome details) participates in the following event(s):
R-HSA-983157 Interaction of E3 with substrate and E2-Ub complex R-HSA-983147 Release of E3 from polyubiquitinated substrate R-HSA-983140 Transfer of Ub from E2 to substrate and release of E2 R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983169 Class I MHC mediated antigen processing & presentation R-HSA-1280218 Adaptive Immune System R-HSA-168256 Immune System