Human Gene HMGN2P46 (uc001zvn.2) Description and Page Index
  Description: Homo sapiens high mobility group nucleosomal binding domain 2 pseudogene 46 (HMGN2P46), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr15:45,803,334-45,848,928 Size: 45,595 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr15:45,839,346-45,848,169 Size: 8,824 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:45,803,334-45,848,928)mRNA (may differ from genome)Protein (172 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblExonPrimerGeneCardsH-INVHGNCHPRD
LynxMGIneXtProtPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: DPCA2_HUMAN
DESCRIPTION: RecName: Full=Putative Dresden prostate carcinoma protein 2; Short=D-PCa-2; AltName: Full=High mobility group nucleosome-binding domain-containing protein 2 pseudogene 46;
TISSUE SPECIFICITY: Very high expression in prostate and prostate cancer. Faint expression in other tissues.
CAUTION: Could be the product of a pseudogene.

-  MalaCards Disease Associations
  MalaCards Gene Search: HMGN2P46
Diseases sorted by gene-association score: prostate cancer (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.90 RPKM in Prostate
Total median expression: 30.87 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -114.70404-0.284 Picture PostScript Text
3' UTR -204.86759-0.270 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q86SG4
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ900944 - Synthetic construct Homo sapiens clone ccsbBroadEn_10338 HMGN2P46 gene, encodes complete protein.
CU693129 - Synthetic construct Homo sapiens gateway clone IMAGE:100018266 3' read SLC30A4 mRNA.
EF632112 - Homo sapiens C15ORF21/ETV1 fusion transcript mRNA, partial sequence.
AK096745 - Homo sapiens cDNA FLJ39426 fis, clone PROST2000505.
JD139414 - Sequence 120438 from Patent EP1572962.
AY271964 - Homo sapiens D-PCa-2 splice variant 1 mRNA, complete cds; alternatively spliced.
AY271965 - Homo sapiens D-PCa-2 mRNA, complete cds; alternatively spliced.
AY271966 - Homo sapiens D-PCa-2 splice variant 2 mRNA, complete cds; alternatively spliced.
AY271967 - Homo sapiens D-PCa-2 splice variant 3 mRNA, complete cds; alternatively spliced.
BC062412 - Homo sapiens cDNA clone IMAGE:6205587, partial cds.
JD295163 - Sequence 276187 from Patent EP1572962.
JD184561 - Sequence 165585 from Patent EP1572962.
BC101266 - Homo sapiens chromosome 15 open reading frame 21, mRNA (cDNA clone IMAGE:40024054), **** WARNING: chimeric clone ****.
JD049943 - Sequence 30967 from Patent EP1572962.
JD490033 - Sequence 471057 from Patent EP1572962.
JD465840 - Sequence 446864 from Patent EP1572962.
DQ581351 - Homo sapiens piRNA piR-49463, complete sequence.
JD181789 - Sequence 162813 from Patent EP1572962.
JD483925 - Sequence 464949 from Patent EP1572962.
JD323731 - Sequence 304755 from Patent EP1572962.
JD442109 - Sequence 423133 from Patent EP1572962.
JD296493 - Sequence 277517 from Patent EP1572962.
JD137186 - Sequence 118210 from Patent EP1572962.
JD068945 - Sequence 49969 from Patent EP1572962.
JD291171 - Sequence 272195 from Patent EP1572962.
JD489347 - Sequence 470371 from Patent EP1572962.
JD409743 - Sequence 390767 from Patent EP1572962.
JD549664 - Sequence 530688 from Patent EP1572962.
L32131 - Homo sapiens (clone XP2E8B) mRNA, partial cds.
JD082361 - Sequence 63385 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AY271967, C15orf21, DPCA2_HUMAN, Q495B5, Q86SG4, Q86SH8, Q8N8I5, uc001zvn.1
UCSC ID: uc001zvn.2
RefSeq Accession: NR_022014
Protein: Q86SG4 (aka DPCA2_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AY271967.1
exon count: 4CDS single in 3' UTR: no RNA size: 1039
ORF size: 519CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 686.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.