Human Gene GVINP1 (uc001meo.4) Description and Page Index
  Description: Homo sapiens GTPase, very large interferon inducible pseudogene 1 (GVINP1), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr11:6,734,381-6,743,110 Size: 8,730 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr11:6,735,842-6,741,268 Size: 5,427 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:6,734,381-6,743,110)mRNA (may differ from genome)Protein (1808 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCLynxMGIneXtProtOMIM
PubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: GVIN1_HUMAN
DESCRIPTION: RecName: Full=Interferon-induced very large GTPase 1; AltName: Full=Interferon-induced very large GTPase pseudogene 1;
SUBCELLULAR LOCATION: Cytoplasm, cytosol (By similarity). Nucleus (By similarity).
SIMILARITY: Belongs to the RHD3 family.
SEQUENCE CAUTION: Sequence=BAB14573.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.63 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 27.27 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -595.901842-0.324 Picture PostScript Text
3' UTR -498.431461-0.341 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  SCOP Domains:
75217 - alpha/beta knot
52540 - P-loop containing nucleoside triphosphate hydrolases

ModBase Predicted Comparative 3D Structure on Q7Z2Y8
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
      
      
  Ensembl   
  Protein Sequence   
  Alignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0005525 GTP binding

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  BX538342 - Homo sapiens mRNA; cDNA DKFZp686C05222 (from clone DKFZp686C05222).
AL834507 - Homo sapiens mRNA; cDNA DKFZp667H0215 (from clone DKFZp667H0215).
JD179001 - Sequence 160025 from Patent EP1572962.
JD434910 - Sequence 415934 from Patent EP1572962.
JD434911 - Sequence 415935 from Patent EP1572962.
JD529703 - Sequence 510727 from Patent EP1572962.
JD529704 - Sequence 510728 from Patent EP1572962.
JD430471 - Sequence 411495 from Patent EP1572962.
JD395429 - Sequence 376453 from Patent EP1572962.
JD401621 - Sequence 382645 from Patent EP1572962.
JD401620 - Sequence 382644 from Patent EP1572962.
JD434909 - Sequence 415933 from Patent EP1572962.
JD376755 - Sequence 357779 from Patent EP1572962.
JD341079 - Sequence 322103 from Patent EP1572962.
JD099964 - Sequence 80988 from Patent EP1572962.
JD183308 - Sequence 164332 from Patent EP1572962.
JD301083 - Sequence 282107 from Patent EP1572962.
JD463153 - Sequence 444177 from Patent EP1572962.
AK023435 - Homo sapiens cDNA FLJ13373 fis, clone PLACE1000749.
JD288687 - Sequence 269711 from Patent EP1572962.
JD038875 - Sequence 19899 from Patent EP1572962.
BX538318 - Homo sapiens mRNA; cDNA DKFZp686B04169 (from clone DKFZp686B04169).
JD040686 - Sequence 21710 from Patent EP1572962.
JD553694 - Sequence 534718 from Patent EP1572962.
JD507884 - Sequence 488908 from Patent EP1572962.
DQ590393 - Homo sapiens piRNA piR-57505, complete sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: A6NFL2, GVIN1, GVIN1_HUMAN, NR_003945, Q7Z2Y8, Q9H8N5
UCSC ID: uc001meo.4
RefSeq Accession: NR_003945
Protein: Q7Z2Y8 (aka GVIN1_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_003945.1
exon count: 1CDS single in 3' UTR: no RNA size: 8741
ORF size: 5427CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 4450.50frame shift in genome: no % Coverage: 99.87
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.