Human Gene TCP11L1 (uc010rei.2) Description and Page Index
  Description: Homo sapiens t-complex 11, testis-specific-like 1 (TCP11L1), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr11:33,061,561-33,095,109 Size: 33,549 Total Exon Count: 10 Strand: +
Coding Region
   Position: hg19 chr11:33,065,320-33,094,222 Size: 28,903 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:33,061,561-33,095,109)mRNA (may differ from genome)Protein (509 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=T-complex protein 11-like protein 1;
SIMILARITY: Belongs to the TCP11 family.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): TCP11L1
CDC HuGE Published Literature: TCP11L1

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.42 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 116.21 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -81.10216-0.375 Picture PostScript Text
3' UTR -225.13887-0.254 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008862 - Tcp11

Pfam Domains:
PF05794 - T-complex protein 11

ModBase Predicted Comparative 3D Structure on Q9NUJ3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005874 microtubule

-  Descriptions from all associated GenBank mRNAs
  AK090646 - Homo sapiens cDNA FLJ33327 fis, clone BNGH42009025, weakly similar to Homo sapiens t-complex 11(TCP11), mRNA.
BC041696 - Homo sapiens t-complex 11 (mouse)-like 1, mRNA (cDNA clone MGC:48773 IMAGE:5756130), complete cds.
BC030582 - Homo sapiens t-complex 11 (mouse)-like 1, mRNA (cDNA clone IMAGE:4830723), with apparent retained intron.
AK002198 - Homo sapiens cDNA FLJ11336 fis, clone PLACE1010661, weakly similar to TESTIS-SPECIFIC PROTEIN PBS13.
KJ899134 - Synthetic construct Homo sapiens clone ccsbBroadEn_08528 TCP11L1 gene, encodes complete protein.
AK021448 - Homo sapiens cDNA FLJ11386 fis, clone HEMBA1000523, weakly similar to TESTIS-SPECIFIC PROTEIN PBS13.
JD447997 - Sequence 429021 from Patent EP1572962.
JD349433 - Sequence 330457 from Patent EP1572962.
JD172293 - Sequence 153317 from Patent EP1572962.
JD184132 - Sequence 165156 from Patent EP1572962.
JD088493 - Sequence 69517 from Patent EP1572962.
JD296098 - Sequence 277122 from Patent EP1572962.
JD250237 - Sequence 231261 from Patent EP1572962.
JD380869 - Sequence 361893 from Patent EP1572962.
JD559614 - Sequence 540638 from Patent EP1572962.
JD284049 - Sequence 265073 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: D3DR01, NM_001145541, NP_060863, Q8IVX4, Q9NUJ3, T11L1_HUMAN
UCSC ID: uc010rei.2
RefSeq Accession: NM_001145541
Protein: Q9NUJ3 (aka T11L1_HUMAN)
CCDS: CCDS7882.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001145541.1
exon count: 10CDS single in 3' UTR: no RNA size: 2633
ORF size: 1530CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3246.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 910# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.