Human Gene C15orf57 (uc001zma.1) Description and Page Index
  Description: Homo sapiens chromosome 15 open reading frame 57 (C15orf57), transcript variant 3, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr15:40,845,298-40,857,252 Size: 11,955 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr15:40,846,170-40,856,979 Size: 10,810 Coding Exon Count: 4 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr15:40,845,298-40,857,252)mRNA (may differ from genome)Protein (194 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
PubMedStanford SOURCETreefamUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 7.11 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 121.55 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -115.80273-0.424 Picture PostScript Text
3' UTR -279.68872-0.321 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF14989 - Coiled-coil domain containing 32

ModBase Predicted Comparative 3D Structure on Q9BV29-2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein Sequence    

-  Descriptions from all associated GenBank mRNAs
  BC012189 - Homo sapiens cDNA clone IMAGE:4644158, partial cds.
AK098781 - Homo sapiens cDNA FLJ25915 fis, clone CBR04830.
AL832032 - Homo sapiens mRNA; cDNA DKFZp451P134 (from clone DKFZp451P134).
BC001673 - Homo sapiens chromosome 15 open reading frame 57, mRNA (cDNA clone MGC:2530 IMAGE:2823236), complete cds.
AK092214 - Homo sapiens cDNA FLJ34895 fis, clone NT2NE2018176.
AX747411 - Sequence 936 from Patent EP1308459.
JD134648 - Sequence 115672 from Patent EP1572962.
JD251044 - Sequence 232068 from Patent EP1572962.
JD224816 - Sequence 205840 from Patent EP1572962.
JD548711 - Sequence 529735 from Patent EP1572962.
JD513056 - Sequence 494080 from Patent EP1572962.
JD166919 - Sequence 147943 from Patent EP1572962.
JD122321 - Sequence 103345 from Patent EP1572962.
JD460733 - Sequence 441757 from Patent EP1572962.
JD104026 - Sequence 85050 from Patent EP1572962.
JD049626 - Sequence 30650 from Patent EP1572962.
AK312842 - Homo sapiens cDNA, FLJ93284.
CU674824 - Synthetic construct Homo sapiens gateway clone IMAGE:100022377 5' read CCDC32 mRNA.
HQ447606 - Synthetic construct Homo sapiens clone IMAGE:100070951; CCSB013389_02 coiled-coil domain containing 32 (CCDC32) gene, encodes complete protein.
KJ895122 - Synthetic construct Homo sapiens clone ccsbBroadEn_04516 C15orf57 gene, encodes complete protein.
AK293079 - Homo sapiens cDNA FLJ77717 complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: CCDC32, NM_001080791, NP_443081, Q9BV29-2
UCSC ID: uc001zma.1
RefSeq Accession: NM_001080791
Protein: Q9BV29-2, splice isoform of Q9BV29 CCDS: CCDS10060.1, CCDS42022.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001080791.1
exon count: 4CDS single in 3' UTR: no RNA size: 1749
ORF size: 585CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1370.00frame shift in genome: no % Coverage: 98.91
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.