Human Gene TMEM238 (uc002qku.3) Description and Page Index
  Description: Homo sapiens transmembrane protein 238 (TMEM238), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:55,890,612-55,895,627 Size: 5,016 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr19:55,895,097-55,895,627 Size: 531 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:55,890,612-55,895,627)mRNA (may differ from genome)Protein (176 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
HGNCLynxMGIneXtProtPubMedStanford SOURCE
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: TM238_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 238;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.94 RPKM in Colon - Transverse
Total median expression: 59.16 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -30.10131-0.230 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15125 - TMEM238 protein family

ModBase Predicted Comparative 3D Structure on C9JI98
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Ensembl   
  Protein Sequence   
  Alignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC052596 - Homo sapiens hypothetical gene supported by BC052596, mRNA (cDNA clone IMAGE:6728287).
JD406576 - Sequence 387600 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C9JI98, NM_001190764, NP_001177693, TM238_HUMAN
UCSC ID: uc002qku.3
RefSeq Accession: NM_001190764
Protein: C9JI98 (aka TM238_HUMAN)
CCDS: CCDS54323.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001190764.1
exon count: 2CDS single in 3' UTR: no RNA size: 711
ORF size: 531CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1259.00frame shift in genome: no % Coverage: 93.11
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.