ID:SMAGP_HUMAN DESCRIPTION: RecName: Full=Small cell adhesion glycoprotein; AltName: Full=Small transmembrane and glycosylated protein; FUNCTION: May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. SUBCELLULAR LOCATION: Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle membrane; Single-pass type III membrane protein. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors. TISSUE SPECIFICITY: Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level). PTM: O-glycosylated. The O-glycan is modified with sialic acid residues. SIMILARITY: Belongs to the SMAGP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q0VAQ4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.