The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on B4DTM5
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK300277 - Homo sapiens cDNA FLJ56869 complete cds. AK301703 - Homo sapiens cDNA FLJ56875 complete cds. AK296301 - Homo sapiens cDNA FLJ56878 complete cds. AK295170 - Homo sapiens cDNA FLJ54462 complete cds. AK303500 - Homo sapiens cDNA FLJ58661 complete cds. AK316459 - Homo sapiens cDNA, FLJ79358 complete cds. AK293635 - Homo sapiens cDNA FLJ59829 complete cds. BC110658 - Homo sapiens cDNA clone IMAGE:6069264, **** WARNING: chimeric clone ****. D86974 - Homo sapiens mRNA for KIAA0220 gene, partial cds. BC094882 - Homo sapiens PI-3-kinase-related kinase SMG-1 isoform 1 homolog, mRNA (cDNA clone MGC:105000 IMAGE:3093162), complete cds. AK294452 - Homo sapiens cDNA FLJ55869 complete cds. AB209632 - Homo sapiens mRNA for PI-3-kinase-related kinase SMG-1 isoform 1homolog protein. BC061522 - Homo sapiens PI-3-kinase-related kinase SMG-1 isoform 1 homolog, mRNA (cDNA clone MGC:70907 IMAGE:6190707), complete cds. BC036263 - Homo sapiens PI-3-kinase-related kinase SMG-1 isoform 1 homolog, mRNA (cDNA clone MGC:9515 IMAGE:3903371), complete cds. AK303607 - Homo sapiens cDNA FLJ61625 complete cds. AK303166 - Homo sapiens cDNA FLJ54505 complete cds. AK303572 - Homo sapiens cDNA FLJ61599 complete cds. JD041122 - Sequence 22146 from Patent EP1572962. AY498718 - Homo sapiens pps22-1 protein mRNA, partial cds. KJ905429 - Synthetic construct Homo sapiens clone ccsbBroadEn_15006 NPIPL3-like gene, encodes complete protein. CU690320 - Synthetic construct Homo sapiens gateway clone IMAGE:100018410 5' read LOC23117 mRNA. JD082959 - Sequence 63983 from Patent EP1572962.