Human Gene RPS17 (uc002bio.1)
Description: Homo sapiens ribosomal protein S17-like (RPS17), mRNA.
Transcript (Including UTRs)
Position: hg19 chr15:83,205,504-83,209,208 Size: 3,705 Total Exon Count: 5 Strand: -
Coding Region
Position: hg19 chr15:83,205,552-83,209,179 Size: 3,628 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: RS17L_HUMAN
DESCRIPTION: RecName: Full=40S ribosomal protein S17-like;
SIMILARITY: Belongs to the ribosomal protein S17e family.
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): RPS17
CDC HuGE Published Literature: RPS17
MalaCards Disease Associations
MalaCards Gene Search: RPS17
Diseases sorted by gene-association score: diamond-blackfan anemia 4 * (930), rps17-related diamond-blackfan anemia * (500), diamond-blackfan anemia * (183), congenital hypoplastic anemia (25), diaphragm disease (18), macrocytic anemia (16), retinitis pigmentosa 49 (15), immune system disease (15), corneal fleck dystrophy (14), stromal dystrophy (11), hepatitis e (11), pure red-cell aplasia (10), necrotizing fasciitis (9), pierre robin syndrome (8), bone deterioration disease (6), physical disorder (6), fasciitis (6), aplastic anemia (2)* = Manually curated disease association
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001210 - Ribosomal_S17e
IPR018273 - Ribosomal_S17e_CS
Pfam Domains: PF00833 - Ribosomal S17
ModBase Predicted Comparative 3D Structure on P0CW22
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC009407 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:19553 IMAGE:4334552), complete cds.BC070222 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:88203 IMAGE:6738383), complete cds.BC071928 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:88613 IMAGE:5090053), complete cds.BC049824 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:59704 IMAGE:6212543), complete cds.BC020453 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone IMAGE:3450232).BC019899 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:29933 IMAGE:3882924), complete cds.AK026570 - Homo sapiens cDNA: FLJ22917 fis, clone KAT06430.BC062715 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:72007 IMAGE:4068842), complete cds.M13932 - Human ribosomal protein S17 mRNA, complete cds.BC022370 - Homo sapiens ribosomal protein S17, mRNA (cDNA clone MGC:23905 IMAGE:4738331), complete cds.AK311951 - Homo sapiens cDNA, FLJ92219, Homo sapiens ribosomal protein S17 (RPS17), mRNA.KJ897506 - Synthetic construct Homo sapiens clone ccsbBroadEn_06900 RPS17 gene, encodes complete protein.CU687068 - Synthetic construct Homo sapiens gateway clone IMAGE:100023030 5' read RPS17 mRNA.KJ905912 - Synthetic construct Homo sapiens clone ccsbBroadEn_15582 RPS17 gene, encodes complete protein.DQ893380 - Synthetic construct clone IMAGE:100006010; FLH199452.01X; RZPDo839A0882D ribosomal protein S17 (RPS17) gene, encodes complete protein.DQ896701 - Synthetic construct Homo sapiens clone IMAGE:100011161; FLH199358.01L; RZPDo839A0881D ribosomal protein S17 (RPS17) gene, encodes complete protein.DQ582527 - Homo sapiens piRNA piR-32639, complete sequence.AB055777 - Homo sapiens mRNA for ribosomal protein S17, partial cds.
Other Names for This Gene
Alternate Gene Symbols: NM_001199057, NP_001185986, P0CW22, RPS17L, RS17L_HUMANUCSC ID: uc002bio.1RefSeq Accession: NM_001199057
Protein: P0CW22
(aka RS17L_HUMAN)
GeneReviews for This Gene
GeneReviews article(s) related to gene RPS17:diamond-b (Diamond-Blackfan Anemia)
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001199057.1
exon count:
5 CDS single in 3' UTR:
no
RNA size:
485
ORF size:
408 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1016.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
2
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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