Human Gene GVINP1 (uc001meo.4) Description and Page Index
  Description: Homo sapiens GTPase, very large interferon inducible pseudogene 1 (GVINP1), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr11:6,734,381-6,743,110 Size: 8,730 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr11:6,735,842-6,741,268 Size: 5,427 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:6,734,381-6,743,110)mRNA (may differ from genome)Protein (1808 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
PubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Interferon-induced very large GTPase 1; AltName: Full=Interferon-induced very large GTPase pseudogene 1;
SUBCELLULAR LOCATION: Cytoplasm, cytosol (By similarity). Nucleus (By similarity).
SIMILARITY: Belongs to the RHD3 family.
SEQUENCE CAUTION: Sequence=BAB14573.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.63 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 27.27 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -595.901842-0.324 Picture PostScript Text
3' UTR -498.431461-0.341 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  SCOP Domains:
75217 - alpha/beta knot
52540 - P-loop containing nucleoside triphosphate hydrolases

ModBase Predicted Comparative 3D Structure on Q7Z2Y8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
  Protein Sequence   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0005525 GTP binding

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

-  Descriptions from all associated GenBank mRNAs
  BX538342 - Homo sapiens mRNA; cDNA DKFZp686C05222 (from clone DKFZp686C05222).
AL834507 - Homo sapiens mRNA; cDNA DKFZp667H0215 (from clone DKFZp667H0215).
JD179001 - Sequence 160025 from Patent EP1572962.
JD434910 - Sequence 415934 from Patent EP1572962.
JD434911 - Sequence 415935 from Patent EP1572962.
JD529703 - Sequence 510727 from Patent EP1572962.
JD529704 - Sequence 510728 from Patent EP1572962.
JD430471 - Sequence 411495 from Patent EP1572962.
JD395429 - Sequence 376453 from Patent EP1572962.
JD401621 - Sequence 382645 from Patent EP1572962.
JD401620 - Sequence 382644 from Patent EP1572962.
JD434909 - Sequence 415933 from Patent EP1572962.
JD376755 - Sequence 357779 from Patent EP1572962.
JD341079 - Sequence 322103 from Patent EP1572962.
JD099964 - Sequence 80988 from Patent EP1572962.
JD183308 - Sequence 164332 from Patent EP1572962.
JD301083 - Sequence 282107 from Patent EP1572962.
JD463153 - Sequence 444177 from Patent EP1572962.
AK023435 - Homo sapiens cDNA FLJ13373 fis, clone PLACE1000749.
JD288687 - Sequence 269711 from Patent EP1572962.
JD038875 - Sequence 19899 from Patent EP1572962.
BX538318 - Homo sapiens mRNA; cDNA DKFZp686B04169 (from clone DKFZp686B04169).
JD040686 - Sequence 21710 from Patent EP1572962.
JD553694 - Sequence 534718 from Patent EP1572962.
JD507884 - Sequence 488908 from Patent EP1572962.
DQ590393 - Homo sapiens piRNA piR-57505, complete sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: A6NFL2, GVIN1, GVIN1_HUMAN, NR_003945, Q7Z2Y8, Q9H8N5
UCSC ID: uc001meo.4
RefSeq Accession: NR_003945
Protein: Q7Z2Y8 (aka GVIN1_HUMAN)

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NR_003945.1
exon count: 1CDS single in 3' UTR: no RNA size: 8741
ORF size: 5427CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 4450.50frame shift in genome: no % Coverage: 99.87
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.