Human Gene SDR9C7 (uc010sqw.2) Description and Page Index
Description: Homo sapiens short chain dehydrogenase/reductase family 9C, member 7 (SDR9C7), mRNA. RefSeq Summary (NM_148897): This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities. [provided by RefSeq, Apr 2010]. ##Evidence-Data-START## Transcript exon combination :: AK122782.1, SRR3476690.1008873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000293502.2/ ENSP00000293502.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## Transcript (Including UTRs) Position: hg19 chr12:57,316,938-57,328,189 Size: 11,252 Total Exon Count: 4 Strand: - Coding Region Position: hg19 chr12:57,317,617-57,328,045 Size: 10,429 Coding Exon Count: 4
ID:DR9C7_HUMAN DESCRIPTION: RecName: Full=Short-chain dehydrogenase/reductase family 9C member 7; EC=1.1.1.-; AltName: Full=Orphan short-chain dehydrogenase/reductase; Short=SDR-O; AltName: Full=RDH-S; FUNCTION: Displays weak conversion of all-trans-retinal to all- trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity. SUBCELLULAR LOCATION: Cytoplasm. Note=Granular distribution in the whole cell. TISSUE SPECIFICITY: Highly expressed in liver. SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8NEX9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
KJ895356 - Synthetic construct Homo sapiens clone ccsbBroadEn_04750 SDR9C7 gene, encodes complete protein. AK122782 - Homo sapiens cDNA FLJ16333 fis, clone TESOP2002150, highly similar to Homo sapiens orphan short-chain dehydrogenase/reductase (SDR-O), mRNA. BC101551 - Homo sapiens short chain dehydrogenase/reductase family 9C, member 7, mRNA (cDNA clone MGC:126600 IMAGE:8069057), complete cds. BC101553 - Homo sapiens short chain dehydrogenase/reductase family 9C, member 7, mRNA (cDNA clone MGC:126602 IMAGE:8069059), complete cds. AY044434 - Homo sapiens retinol dehydrogenase similar protein (RDHS) mRNA, complete cds.