ID:ZNT9_HUMAN DESCRIPTION: RecName: Full=Zinc transporter 9; Short=ZnT-9; AltName: Full=Human embryonic lung protein; Short=HuEL; AltName: Full=Solute carrier family 30 member 9; FUNCTION: Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity). SUBUNIT: Interacts with GRIP1, ESR1 and AR (By similarity). SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). Nucleus. TISSUE SPECIFICITY: Ubiquitously expressed in fetal and adult tissues and cancer cell lines. SIMILARITY: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. SEQUENCE CAUTION: Sequence=AAP83846.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites; Sequence=AAY40966.1; Type=Erroneous gene model prediction;
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): SLC30A9 CDC HuGE Published Literature: SLC30A9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6PML9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.