ID:ELOF1_HUMAN DESCRIPTION: RecName: Full=Transcription elongation factor 1 homolog; FUNCTION: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions (By similarity). SUBCELLULAR LOCATION: Nucleus (By similarity). SIMILARITY: Belongs to the ELOF1 family.
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): ELOF1 CDC HuGE Published Literature: ELOF1 Positive Disease Associations: Multiple Sclerosis Related Studies:
Multiple Sclerosis Sergio E Baranzini et al. Human molecular genetics 2009, Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis., Human molecular genetics.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF05129 - Transcription elongation factor Elf1 like
ModBase Predicted Comparative 3D Structure on P60002
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.