Human Gene SZRD1 (uc001aym.5) Description and Page Index
Description: Homo sapiens SUZ RNA binding domain containing 1 (SZRD1), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:16,693,525-16,724,643 Size: 31,119 Total Exon Count: 4 Strand: +
Position: hg19 chr1:16,693,753-16,721,635 Size: 27,883 Coding Exon Count: 4
Data last updated: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=SUZ domain-containing protein 1; AltName: Full=Putative MAPK-activating protein PM18/PM20/PM22;
SIMILARITY: Belongs to the SZRD1 family. SIMILARITY: Contains 1 SUZ domain. SEQUENCE CAUTION: Sequence=CAB43245.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAC82500.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR024771 - SUZ
IPR024642 - SUZ-C
Pfam Domains: PF12752 - SUZ domain
PF12901 - SUZ-C motif
ModBase Predicted Comparative 3D Structure on Q7Z422
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
BC023988 - Homo sapiens chromosome 1 open reading frame 144, mRNA (cDNA clone MGC:24215 IMAGE:3825796), complete cds. BX640985 - Homo sapiens mRNA; cDNA DKFZp686E15252 (from clone DKFZp686E15252). AJ295987 - Homo sapiens mRNA for hypothetical protein (ORF1), clone Telethon(Italy_B41)_Strait01448_FL406. AK297926 - Homo sapiens cDNA FLJ54298 complete cds. AK298576 - Homo sapiens cDNA FLJ51932 complete cds. AL050028 - Homo sapiens mRNA; cDNA DKFZp566C0424 (from clone DKFZp566C0424); partial cds. AB097046 - Homo sapiens mRNA for putative MAPK activating protein, complete cds, clone: PM22. AB097042 - Homo sapiens mRNA for putative MAPK activating protein, complete cds, clone: PM18. AB097043 - Homo sapiens mRNA for putative MAPK activating protein, complete cds, clone: PM19. AK308787 - Homo sapiens cDNA, FLJ98828. AK316205 - Homo sapiens cDNA, FLJ79104 complete cds. BC065538 - Homo sapiens chromosome 1 open reading frame 144, mRNA (cDNA clone MGC:70432 IMAGE:6053254), complete cds. AB097044 - Homo sapiens mRNA for putative MAPK activating protein, complete cds, clone: PM20. AB097045 - Homo sapiens mRNA for putative MAPK activating protein, complete cds, clone: PM21. HQ448631 - Synthetic construct Homo sapiens clone IMAGE:100072070; CCSB012289_01 chromosome 1 open reading frame 144 (C1orf144) gene, encodes complete protein. KJ893521 - Synthetic construct Homo sapiens clone ccsbBroadEn_02915 C1orf144 gene, encodes complete protein. BC010631 - Homo sapiens chromosome 1 open reading frame 144, mRNA (cDNA clone IMAGE:3867552), with apparent retained intron. JD129922 - Sequence 110946 from Patent EP1572962. JD409863 - Sequence 390887 from Patent EP1572962. JD234405 - Sequence 215429 from Patent EP1572962. JD076979 - Sequence 58003 from Patent EP1572962. JD493578 - Sequence 474602 from Patent EP1572962. JD539057 - Sequence 520081 from Patent EP1572962. JD044313 - Sequence 25337 from Patent EP1572962. JD101620 - Sequence 82644 from Patent EP1572962. JD301588 - Sequence 282612 from Patent EP1572962. JD115829 - Sequence 96853 from Patent EP1572962. JD389731 - Sequence 370755 from Patent EP1572962. JD343356 - Sequence 324380 from Patent EP1572962. JD493937 - Sequence 474961 from Patent EP1572962. JD132358 - Sequence 113382 from Patent EP1572962. JD515616 - Sequence 496640 from Patent EP1572962. JD146669 - Sequence 127693 from Patent EP1572962. DQ595013 - Homo sapiens piRNA piR-61125, complete sequence. AK098272 - Homo sapiens cDNA FLJ40953 fis, clone UTERU2010417. DQ588460 - Homo sapiens piRNA piR-55572, complete sequence. AL832937 - Homo sapiens mRNA; cDNA DKFZp666F1410 (from clone DKFZp666F1410).
Other Names for This Gene
Alternate Gene Symbols: A8MXJ2, C1orf144, NM_001114600, NP_001108072, Q7Z422, Q7Z424, Q8IVM2, Q8TBV3, Q9Y403, SZRD1_HUMAN, uc001aym.4 UCSC ID: uc001aym.5 RefSeq Accession: NM_001114600
(aka SZRD1_HUMAN) Q7Z422
CCDS: CCDS44065.1, CCDS60000.1
Gene Model Information
4 CDS single in 3' UTR:
459 CDS single in intron:
Alignment % ID:
985.00 frame shift in genome:
has start codon:
stop codon in genome:
# of Alignments:
has end codon:
# AT/AC introns
end bleed into intron:
3078 # strange splices:
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.