Human Gene LOC493754 (uc010lac.3) Description and Page Index
  Description: Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 pseudogene (LOC493754), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr7:65,993,455-66,057,371 Size: 63,917 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg19 chr7:65,996,774-66,010,629 Size: 13,856 Coding Exon Count: 3 

Page IndexSequence and LinksGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:65,993,455-66,057,371)mRNA (may differ from genome)Protein (117 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblExonPrimerGeneCardsGeneNetworkH-INVLynx
MGIPubMedStanford SOURCEUniProtKB

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 7.72 RPKM in Testis
Total median expression: 130.28 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -206.30591-0.349 Picture PostScript Text
3' UTR -1353.323319-0.408 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on A4D2L9
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK024371 - Homo sapiens cDNA FLJ14309 fis, clone PLACE3000221.
BC029469 - Homo sapiens cDNA clone IMAGE:4722553.
JD254770 - Sequence 235794 from Patent EP1572962.
JD435466 - Sequence 416490 from Patent EP1572962.
JD342264 - Sequence 323288 from Patent EP1572962.
JD242958 - Sequence 223982 from Patent EP1572962.
JD364148 - Sequence 345172 from Patent EP1572962.
JD139565 - Sequence 120589 from Patent EP1572962.
JD139564 - Sequence 120588 from Patent EP1572962.
JD310513 - Sequence 291537 from Patent EP1572962.
JD310512 - Sequence 291536 from Patent EP1572962.
JD463119 - Sequence 444143 from Patent EP1572962.
JD213093 - Sequence 194117 from Patent EP1572962.
JD337598 - Sequence 318622 from Patent EP1572962.
JD533858 - Sequence 514882 from Patent EP1572962.
JD407580 - Sequence 388604 from Patent EP1572962.
JD542923 - Sequence 523947 from Patent EP1572962.
JD371287 - Sequence 352311 from Patent EP1572962.
JD256790 - Sequence 237814 from Patent EP1572962.
JD560958 - Sequence 541982 from Patent EP1572962.
JD514449 - Sequence 495473 from Patent EP1572962.
JD165235 - Sequence 146259 from Patent EP1572962.
JD414497 - Sequence 395521 from Patent EP1572962.
JD524713 - Sequence 505737 from Patent EP1572962.
JD352488 - Sequence 333512 from Patent EP1572962.
JD367506 - Sequence 348530 from Patent EP1572962.
JD536381 - Sequence 517405 from Patent EP1572962.
JD234030 - Sequence 215054 from Patent EP1572962.
JD528130 - Sequence 509154 from Patent EP1572962.
JD133341 - Sequence 114365 from Patent EP1572962.
JD254422 - Sequence 235446 from Patent EP1572962.
JD328777 - Sequence 309801 from Patent EP1572962.
JD375374 - Sequence 356398 from Patent EP1572962.
JD136853 - Sequence 117877 from Patent EP1572962.
JD416809 - Sequence 397833 from Patent EP1572962.
JD135077 - Sequence 116101 from Patent EP1572962.
JD551858 - Sequence 532882 from Patent EP1572962.
JD169079 - Sequence 150103 from Patent EP1572962.
JD360061 - Sequence 341085 from Patent EP1572962.
JD101595 - Sequence 82619 from Patent EP1572962.
JD275065 - Sequence 256089 from Patent EP1572962.
JD326130 - Sequence 307154 from Patent EP1572962.
JD418866 - Sequence 399890 from Patent EP1572962.
BC037920 - Homo sapiens cDNA clone IMAGE:5278284.
JD517210 - Sequence 498234 from Patent EP1572962.
JD105014 - Sequence 86038 from Patent EP1572962.
JD517209 - Sequence 498233 from Patent EP1572962.
JD495338 - Sequence 476362 from Patent EP1572962.
JD221398 - Sequence 202422 from Patent EP1572962.
JD220068 - Sequence 201092 from Patent EP1572962.
JD544915 - Sequence 525939 from Patent EP1572962.
JD283420 - Sequence 264444 from Patent EP1572962.
JD308823 - Sequence 289847 from Patent EP1572962.
JD093863 - Sequence 74887 from Patent EP1572962.
JD311785 - Sequence 292809 from Patent EP1572962.
JD304114 - Sequence 285138 from Patent EP1572962.
JD311786 - Sequence 292810 from Patent EP1572962.
JD304115 - Sequence 285139 from Patent EP1572962.
JD304116 - Sequence 285140 from Patent EP1572962.
JD339100 - Sequence 320124 from Patent EP1572962.
JD397047 - Sequence 378071 from Patent EP1572962.
JD311784 - Sequence 292808 from Patent EP1572962.
JD105090 - Sequence 86114 from Patent EP1572962.
JD142460 - Sequence 123484 from Patent EP1572962.
JD513918 - Sequence 494942 from Patent EP1572962.
JD256540 - Sequence 237564 from Patent EP1572962.
JD379668 - Sequence 360692 from Patent EP1572962.
JD094116 - Sequence 75140 from Patent EP1572962.
JD379667 - Sequence 360691 from Patent EP1572962.
JD120558 - Sequence 101582 from Patent EP1572962.
JD120559 - Sequence 101583 from Patent EP1572962.
JD148683 - Sequence 129707 from Patent EP1572962.
JD414809 - Sequence 395833 from Patent EP1572962.
JD392304 - Sequence 373328 from Patent EP1572962.
JD547279 - Sequence 528303 from Patent EP1572962.
JD127097 - Sequence 108121 from Patent EP1572962.
JD402728 - Sequence 383752 from Patent EP1572962.
JD521612 - Sequence 502636 from Patent EP1572962.
JD292023 - Sequence 273047 from Patent EP1572962.
JD403013 - Sequence 384037 from Patent EP1572962.
JD250031 - Sequence 231055 from Patent EP1572962.
JD353891 - Sequence 334915 from Patent EP1572962.
JD484312 - Sequence 465336 from Patent EP1572962.
JD535008 - Sequence 516032 from Patent EP1572962.
JD545983 - Sequence 527007 from Patent EP1572962.
JD446161 - Sequence 427185 from Patent EP1572962.
JD533605 - Sequence 514629 from Patent EP1572962.
JD170532 - Sequence 151556 from Patent EP1572962.
JD475054 - Sequence 456078 from Patent EP1572962.
JD214332 - Sequence 195356 from Patent EP1572962.
JD156382 - Sequence 137406 from Patent EP1572962.
JD353288 - Sequence 334312 from Patent EP1572962.
JD049299 - Sequence 30323 from Patent EP1572962.
JD213550 - Sequence 194574 from Patent EP1572962.
JD406450 - Sequence 387474 from Patent EP1572962.
JD054498 - Sequence 35522 from Patent EP1572962.
JD041591 - Sequence 22615 from Patent EP1572962.
JD037013 - Sequence 18037 from Patent EP1572962.
JD085503 - Sequence 66527 from Patent EP1572962.
JD294580 - Sequence 275604 from Patent EP1572962.
JD344895 - Sequence 325919 from Patent EP1572962.
JD140809 - Sequence 121833 from Patent EP1572962.
JD137757 - Sequence 118781 from Patent EP1572962.
JD099150 - Sequence 80174 from Patent EP1572962.
JD189487 - Sequence 170511 from Patent EP1572962.
JD285561 - Sequence 266585 from Patent EP1572962.
JD079911 - Sequence 60935 from Patent EP1572962.
JD311270 - Sequence 292294 from Patent EP1572962.
JD414722 - Sequence 395746 from Patent EP1572962.
JD311269 - Sequence 292293 from Patent EP1572962.
JD069712 - Sequence 50736 from Patent EP1572962.
JD513890 - Sequence 494914 from Patent EP1572962.
JD414343 - Sequence 395367 from Patent EP1572962.
JD379575 - Sequence 360599 from Patent EP1572962.
JD120499 - Sequence 101523 from Patent EP1572962.
JD513889 - Sequence 494913 from Patent EP1572962.
JD414342 - Sequence 395366 from Patent EP1572962.
JD120498 - Sequence 101522 from Patent EP1572962.
JD414720 - Sequence 395744 from Patent EP1572962.
JD321644 - Sequence 302668 from Patent EP1572962.
JD342494 - Sequence 323518 from Patent EP1572962.
JD204681 - Sequence 185705 from Patent EP1572962.
JD279003 - Sequence 260027 from Patent EP1572962.
JD295045 - Sequence 276069 from Patent EP1572962.
JD285449 - Sequence 266473 from Patent EP1572962.
JD072253 - Sequence 53277 from Patent EP1572962.
JD345620 - Sequence 326644 from Patent EP1572962.
JD478698 - Sequence 459722 from Patent EP1572962.
JD407718 - Sequence 388742 from Patent EP1572962.
JD256866 - Sequence 237890 from Patent EP1572962.
JD258863 - Sequence 239887 from Patent EP1572962.
JD353154 - Sequence 334178 from Patent EP1572962.
JD353151 - Sequence 334175 from Patent EP1572962.
JD353149 - Sequence 334173 from Patent EP1572962.
JD523096 - Sequence 504120 from Patent EP1572962.
JD161663 - Sequence 142687 from Patent EP1572962.
JD527720 - Sequence 508744 from Patent EP1572962.
JD153320 - Sequence 134344 from Patent EP1572962.
JD457650 - Sequence 438674 from Patent EP1572962.
JD198489 - Sequence 179513 from Patent EP1572962.
JD140645 - Sequence 121669 from Patent EP1572962.
JD293538 - Sequence 274562 from Patent EP1572962.
JD457649 - Sequence 438673 from Patent EP1572962.
JD122102 - Sequence 103126 from Patent EP1572962.
JD122103 - Sequence 103127 from Patent EP1572962.
JD293537 - Sequence 274561 from Patent EP1572962.
JD457648 - Sequence 438672 from Patent EP1572962.
JD227654 - Sequence 208678 from Patent EP1572962.
JD270561 - Sequence 251585 from Patent EP1572962.
JD457647 - Sequence 438671 from Patent EP1572962.
JD405640 - Sequence 386664 from Patent EP1572962.
JD547682 - Sequence 528706 from Patent EP1572962.
JD547681 - Sequence 528705 from Patent EP1572962.
JD161662 - Sequence 142686 from Patent EP1572962.
JD300858 - Sequence 281882 from Patent EP1572962.
JD505921 - Sequence 486945 from Patent EP1572962.
JD448590 - Sequence 429614 from Patent EP1572962.
JD317986 - Sequence 299010 from Patent EP1572962.
JD330760 - Sequence 311784 from Patent EP1572962.
JD565989 - Sequence 547013 from Patent EP1572962.
JD064002 - Sequence 45026 from Patent EP1572962.
JD441157 - Sequence 422181 from Patent EP1572962.
JD064001 - Sequence 45025 from Patent EP1572962.
JD441156 - Sequence 422180 from Patent EP1572962.
JD183085 - Sequence 164109 from Patent EP1572962.
JD329974 - Sequence 310998 from Patent EP1572962.
JD317161 - Sequence 298185 from Patent EP1572962.
JD322425 - Sequence 303449 from Patent EP1572962.
JD070407 - Sequence 51431 from Patent EP1572962.
JD150280 - Sequence 131304 from Patent EP1572962.
JD425873 - Sequence 406897 from Patent EP1572962.
JD255732 - Sequence 236756 from Patent EP1572962.
JD212185 - Sequence 193209 from Patent EP1572962.
JD463287 - Sequence 444311 from Patent EP1572962.
JD535676 - Sequence 516700 from Patent EP1572962.
JD110447 - Sequence 91471 from Patent EP1572962.
JD248830 - Sequence 229854 from Patent EP1572962.
JD084930 - Sequence 65954 from Patent EP1572962.
JD281607 - Sequence 262631 from Patent EP1572962.
JD279337 - Sequence 260361 from Patent EP1572962.
JD526118 - Sequence 507142 from Patent EP1572962.
JD291203 - Sequence 272227 from Patent EP1572962.
JD107045 - Sequence 88069 from Patent EP1572962.
JD358564 - Sequence 339588 from Patent EP1572962.
JD118835 - Sequence 99859 from Patent EP1572962.
JD151740 - Sequence 132764 from Patent EP1572962.
JD228568 - Sequence 209592 from Patent EP1572962.
JD161893 - Sequence 142917 from Patent EP1572962.
AK310370 - Homo sapiens cDNA, FLJ17412.
AK310548 - Homo sapiens cDNA, FLJ17590.
JD480966 - Sequence 461990 from Patent EP1572962.
JD457759 - Sequence 438783 from Patent EP1572962.
JD465836 - Sequence 446860 from Patent EP1572962.
JD437179 - Sequence 418203 from Patent EP1572962.
JD491779 - Sequence 472803 from Patent EP1572962.
JD180432 - Sequence 161456 from Patent EP1572962.
JD193628 - Sequence 174652 from Patent EP1572962.
JD387689 - Sequence 368713 from Patent EP1572962.
JD426504 - Sequence 407528 from Patent EP1572962.
JD321814 - Sequence 302838 from Patent EP1572962.
JD331245 - Sequence 312269 from Patent EP1572962.
JD316232 - Sequence 297256 from Patent EP1572962.
JD166896 - Sequence 147920 from Patent EP1572962.
JD400436 - Sequence 381460 from Patent EP1572962.
JD449807 - Sequence 430831 from Patent EP1572962.
JD452877 - Sequence 433901 from Patent EP1572962.
JD295053 - Sequence 276077 from Patent EP1572962.
JD057648 - Sequence 38672 from Patent EP1572962.
AK296922 - Homo sapiens cDNA FLJ59924 complete cds.
BC103766 - Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 pseudogene, mRNA (cDNA clone IMAGE:6068172).
AK126730 - Homo sapiens cDNA FLJ44776 fis, clone BRACE3034993.
BC057835 - Homo sapiens cDNA clone IMAGE:30344585, **** WARNING: chimeric clone ****.
BC067867 - Homo sapiens cDNA clone IMAGE:30344560, **** WARNING: chimeric clone ****.
AK054923 - Homo sapiens cDNA FLJ30361 fis, clone BRACE2007764.
BC080520 - Homo sapiens cDNA clone IMAGE:3534351, **** WARNING: chimeric clone ****.
MG828726 - Homo sapiens clone TCONS_00226654 lncRNA, complete sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: A4D2L9, A4D2L9_HUMAN, AK310370, LOC401365, tcag7.870, uc010lac.2
UCSC ID: uc010lac.3
RefSeq Accession: NR_002933
Protein: A4D2L9

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK310370.1
exon count: 6CDS single in 3' UTR: no RNA size: 1460
ORF size: 354CDS single in intron: no Alignment % ID: 99.93
txCdsPredict score: 622.00frame shift in genome: no % Coverage: 99.93
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 3323# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.