Human Gene AMMECR1L (uc002tpl.3) Description and Page Index
  Description: Homo sapiens AMMECR1-like (AMMECR1L), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr2:128,619,207-128,642,434 Size: 23,228 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg19 chr2:128,622,668-128,631,808 Size: 9,141 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:128,619,207-128,642,434)mRNA (may differ from genome)Protein (310 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: AMERL_HUMAN
DESCRIPTION: RecName: Full=AMMECR1-like protein;
SIMILARITY: Contains 1 AMMECR1 domain.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.64 RPKM in Testis
Total median expression: 365.85 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -69.31251-0.276 Picture PostScript Text
3' UTR -1153.933461-0.333 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR023473 - AMMECR1
IPR002733 - AMMECR1_domain

Pfam Domains:
PF01871 - AMMECR1

ModBase Predicted Comparative 3D Structure on Q6DCA0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AL137415 - Homo sapiens mRNA; cDNA DKFZp434O172 (from clone DKFZp434O172).
BC084552 - Homo sapiens cDNA clone IMAGE:6212324.
BC004208 - Homo sapiens hypothetical protein MGC4268, mRNA (cDNA clone IMAGE:3532352), partial cds.
AK024993 - Homo sapiens cDNA: FLJ21340 fis, clone COL02623.
BC016181 - Homo sapiens AMME chromosomal region gene 1-like, mRNA (cDNA clone MGC:20482 IMAGE:4644159), complete cds.
BC078174 - Homo sapiens AMME chromosomal region gene 1-like, mRNA (cDNA clone MGC:88063 IMAGE:6012672), complete cds.
LF385240 - JP 2014500723-A/192743: Polycomb-Associated Non-Coding RNAs.
JD301209 - Sequence 282233 from Patent EP1572962.
JD235344 - Sequence 216368 from Patent EP1572962.
BC067124 - Homo sapiens cDNA clone IMAGE:6159192, partial cds.
AK026685 - Homo sapiens cDNA: FLJ23032 fis, clone LNG01938.
JD313447 - Sequence 294471 from Patent EP1572962.
JD488338 - Sequence 469362 from Patent EP1572962.
JD146005 - Sequence 127029 from Patent EP1572962.
JD130686 - Sequence 111710 from Patent EP1572962.
JD242468 - Sequence 223492 from Patent EP1572962.
JD060323 - Sequence 41347 from Patent EP1572962.
JD112848 - Sequence 93872 from Patent EP1572962.
LF342912 - JP 2014500723-A/150415: Polycomb-Associated Non-Coding RNAs.
JD234270 - Sequence 215294 from Patent EP1572962.
JD140384 - Sequence 121408 from Patent EP1572962.
AK095871 - Homo sapiens cDNA FLJ38552 fis, clone HCHON2002241.
LF342911 - JP 2014500723-A/150414: Polycomb-Associated Non-Coding RNAs.
DQ600924 - Homo sapiens piRNA piR-38990, complete sequence.
LF342910 - JP 2014500723-A/150413: Polycomb-Associated Non-Coding RNAs.
LF342909 - JP 2014500723-A/150412: Polycomb-Associated Non-Coding RNAs.
LF383489 - JP 2014500723-A/190992: Polycomb-Associated Non-Coding RNAs.
AK304145 - Homo sapiens cDNA FLJ52670 complete cds, moderately similar to AMME syndrome candidate gene 1 protein.
HQ447546 - Synthetic construct Homo sapiens clone IMAGE:100070885; CCSB014666_01 AMME chromosomal region gene 1-like (AMMECR1L) gene, encodes complete protein.
KJ894888 - Synthetic construct Homo sapiens clone ccsbBroadEn_04282 AMMECR1L gene, encodes complete protein.
CU687324 - Synthetic construct Homo sapiens gateway clone IMAGE:100022907 5' read AMMECR1L mRNA.
MA620817 - JP 2018138019-A/192743: Polycomb-Associated Non-Coding RNAs.
MA578489 - JP 2018138019-A/150415: Polycomb-Associated Non-Coding RNAs.
MA578488 - JP 2018138019-A/150414: Polycomb-Associated Non-Coding RNAs.
MA578487 - JP 2018138019-A/150413: Polycomb-Associated Non-Coding RNAs.
MA578486 - JP 2018138019-A/150412: Polycomb-Associated Non-Coding RNAs.
MA619066 - JP 2018138019-A/190992: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: AMERL_HUMAN, B4E276, NM_031445, NP_113633, Q6DCA0
UCSC ID: uc002tpl.3
RefSeq Accession: NM_031445
Protein: Q6DCA0 (aka AMERL_HUMAN)
CCDS: CCDS2152.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_031445.2
exon count: 8CDS single in 3' UTR: no RNA size: 4698
ORF size: 933CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1874.00frame shift in genome: no % Coverage: 98.87
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.