Human Gene C14orf177 (uc001yfz.2) Description and Page Index
  Description: Homo sapiens chromosome 14 open reading frame 177 (C14orf177), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr14:99,177,950-99,184,103 Size: 6,154 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr14:99,182,529-99,183,611 Size: 1,083 Coding Exon Count: 2 

Page IndexSequence and LinksGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr14:99,177,950-99,184,103)mRNA (may differ from genome)Protein (125 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
HPRDLynxMGIneXtProtPubMedStanford SOURCE

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.61 RPKM in Testis
Total median expression: 0.61 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -124.73419-0.298 Picture PostScript Text
3' UTR -143.70492-0.292 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q52M58
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  AK098639 - Homo sapiens cDNA FLJ25773 fis, clone TST06517.
JD410845 - Sequence 391869 from Patent EP1572962.
JD553700 - Sequence 534724 from Patent EP1572962.
JD522680 - Sequence 503704 from Patent EP1572962.
JD484851 - Sequence 465875 from Patent EP1572962.
JD273493 - Sequence 254517 from Patent EP1572962.
JD184947 - Sequence 165971 from Patent EP1572962.
BC093661 - Homo sapiens chromosome 14 open reading frame 177, mRNA (cDNA clone MGC:120696 IMAGE:7939506), complete cds.
JD088606 - Sequence 69630 from Patent EP1572962.
JD274146 - Sequence 255170 from Patent EP1572962.
KJ900552 - Synthetic construct Homo sapiens clone ccsbBroadEn_09946 C14orf177 gene, encodes complete protein.
JD110377 - Sequence 91401 from Patent EP1572962.
JD314265 - Sequence 295289 from Patent EP1572962.
JD440345 - Sequence 421369 from Patent EP1572962.
JD500822 - Sequence 481846 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CN177_HUMAN, NM_182560, NP_872366, Q52M58, Q8N7D2
UCSC ID: uc001yfz.2
RefSeq Accession: NM_182560
Protein: Q52M58 (aka CN177_HUMAN)
CCDS: CCDS9948.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_182560.2
exon count: 4CDS single in 3' UTR: no RNA size: 1289
ORF size: 378CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 516.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.