Human Gene MCTS1 (uc011mub.2) Description and Page Index
  Description: Homo sapiens malignant T cell amplified sequence 1 (MCTS1), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chrX:119,738,552-119,755,016 Size: 16,465 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chrX:119,738,709-119,746,119 Size: 7,411 Coding Exon Count: 6 

Page IndexSequence and LinksCTDGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chrX:119,738,552-119,755,016)mRNA (may differ from genome)Protein (182 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
OMIMPubMedStanford SOURCETreefamUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 16.99 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 357.71 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -44.90157-0.286 Picture PostScript Text
3' UTR -2988.778897-0.336 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF01472 - PUA domain

SCOP Domains:
88697 - PUA domain-like

ModBase Predicted Comparative 3D Structure on Q9ULC4-3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AK311993 - Homo sapiens cDNA, FLJ92266, Homo sapiens malignant T cell amplified sequence 1 (MCTS1), mRNA.
AB034206 - Homo sapiens MCT-1 mRNA, complete cds.
BC095461 - Homo sapiens malignant T cell amplified sequence 1, mRNA (cDNA clone MGC:111352 IMAGE:30557789), complete cds.
FW340078 - Screening.
BC001013 - Homo sapiens malignant T cell amplified sequence 1, mRNA (cDNA clone MGC:1187 IMAGE:3344210), complete cds.
CU674498 - Synthetic construct Homo sapiens gateway clone IMAGE:100017978 5' read MCTS1 mRNA.
HQ448721 - Synthetic construct Homo sapiens clone IMAGE:100072166; CCSB007999_01 malignant T cell amplified sequence 1 (MCTS1) gene, encodes complete protein.
KJ893662 - Synthetic construct Homo sapiens clone ccsbBroadEn_03056 MCTS1 gene, encodes complete protein.
AY364258 - Homo sapiens clone peg2135 MCT1 (MCT1) mRNA, complete cds.
AK294834 - Homo sapiens cDNA FLJ59683 complete cds, highly similar to Homo sapiens malignant T cell amplified sequence 1 (MCTS1), mRNA.
JD561741 - Sequence 542765 from Patent EP1572962.
JD263868 - Sequence 244892 from Patent EP1572962.
JD454884 - Sequence 435908 from Patent EP1572962.
JD242906 - Sequence 223930 from Patent EP1572962.
JD242907 - Sequence 223931 from Patent EP1572962.
JD507406 - Sequence 488430 from Patent EP1572962.
JD507407 - Sequence 488431 from Patent EP1572962.
JD064637 - Sequence 45661 from Patent EP1572962.
JD115402 - Sequence 96426 from Patent EP1572962.
JD364149 - Sequence 345173 from Patent EP1572962.
JD254711 - Sequence 235735 from Patent EP1572962.
JD312118 - Sequence 293142 from Patent EP1572962.
JD346598 - Sequence 327622 from Patent EP1572962.
JD285594 - Sequence 266618 from Patent EP1572962.
AK096956 - Homo sapiens cDNA FLJ39637 fis, clone SMINT2003003.
AF456465 - Homo sapiens hypothetical protein mRNA, complete cds.
JD558235 - Sequence 539259 from Patent EP1572962.
JD564286 - Sequence 545310 from Patent EP1572962.
JD558236 - Sequence 539260 from Patent EP1572962.
JD339854 - Sequence 320878 from Patent EP1572962.
JD470729 - Sequence 451753 from Patent EP1572962.
JD135712 - Sequence 116736 from Patent EP1572962.
JD565945 - Sequence 546969 from Patent EP1572962.
JD238302 - Sequence 219326 from Patent EP1572962.
JD238303 - Sequence 219327 from Patent EP1572962.
JD243161 - Sequence 224185 from Patent EP1572962.
JD496045 - Sequence 477069 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: MCT1, NM_001137554, NP_001131026, Q9ULC4-3
UCSC ID: uc011mub.2
RefSeq Accession: NM_001137554
Protein: Q9ULC4-3, splice isoform of Q9ULC4 CCDS: CCDS48160.1, CCDS14601.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001137554.1
exon count: 6CDS single in 3' UTR: no RNA size: 9617
ORF size: 549CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1283.00frame shift in genome: no % Coverage: 99.85
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.