Description: Homo sapiens MAD2L1 binding protein (MAD2L1BP), transcript variant 1, mRNA. RefSeq Summary (NM_001003690): The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]. Transcript (Including UTRs) Position: hg19 chr6:43,597,279-43,608,688 Size: 11,410 Total Exon Count: 4 Strand: + Coding Region Position: hg19 chr6:43,597,487-43,608,270 Size: 10,784 Coding Exon Count: 4
ID:E9PAT7_HUMAN DESCRIPTION: SubName: Full=MAD2L1-binding protein; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF06581 - Mad1 and Cdc20-bound-Mad2 binding
ModBase Predicted Comparative 3D Structure on E9PAT7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
