Human Gene EEF1AKNMT (uc001ghz.3)
Description: Homo sapiens methyltransferase like 13 (EEF1AKNMT), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:171,750,761-171,766,856 Size: 16,096 Total Exon Count: 8 Strand: +
Coding Region
Position: hg19 chr1:171,751,108-171,765,896 Size: 14,789 Coding Exon Count: 8
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: MET13_HUMAN
DESCRIPTION: RecName: Full=Methyltransferase-like protein 13; EC=2.1.1.-;
SIMILARITY: Belongs to the methyltransferase superfamily.SEQUENCE CAUTION: Sequence=BAA74882.2; Type=Erroneous initiation; Sequence=BAD97213.1; Type=Erroneous initiation;
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR013216 - Methyltransf_11
Pfam Domains: PF01564 - Spermine/spermidine synthase domain
PF08241 - Methyltransferase domain
PF13649 - Methyltransferase domain
PF13847 - Methyltransferase domain
SCOP Domains: 51735 - NAD(P)-binding Rossmann-fold domains
53335 - S-adenosyl-L-methionine-dependent methyltransferases
ModBase Predicted Comparative 3D Structure on Q8N6R0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK304471 - Homo sapiens cDNA FLJ56024 complete cds.AK223493 - Homo sapiens mRNA for KIAA0859 protein (Fragment) variant, clone: FCC120A05.AK291740 - Homo sapiens cDNA FLJ78423 complete cds.AK027621 - Homo sapiens cDNA FLJ14715 fis, clone NT2RP3001119.AF132936 - Homo sapiens CGI-01 protein mRNA, complete cds.AB242174 - Homo sapiens feat mRNA for antiapoptotic protein FEAT, complete cds.AL049669 - Human gene from PAC 612B18, chromosome 1.AK027552 - Homo sapiens cDNA FLJ14646 fis, clone NT2RP2001883, highly similar to Homo sapiens CGI-01 protein mRNA.AB242175 - Homo sapiens feat mRNA for antiapoptotic protein FEAT, complete cds.JD310616 - Sequence 291640 from Patent EP1572962.JD541400 - Sequence 522424 from Patent EP1572962.AB020666 - Homo sapiens KIAA0859 mRNA for KIAA0859 protein.BC029083 - Homo sapiens methyltransferase like 13, mRNA (cDNA clone MGC:21094 IMAGE:4509086), complete cds.JD538490 - Sequence 519514 from Patent EP1572962.AB384020 - Synthetic construct DNA, clone: pF1KSDA0859, Homo sapiens KIAA0859 gene for KIAA0859 protein, complete cds, without stop codon, in Flexi system.KJ904757 - Synthetic construct Homo sapiens clone ccsbBroadEn_14151 METTL13-like gene, encodes complete protein.AK027886 - Homo sapiens cDNA FLJ14980 fis, clone Y79AA1000181, highly similar to Homo sapiens CGI-01 protein mRNA.AK074552 - Homo sapiens cDNA FLJ90071 fis, clone HEMBA1004067.AK129561 - Homo sapiens cDNA FLJ26050 fis, clone PRS02782.DQ576381 - Homo sapiens piRNA piR-44493, complete sequence.AK001172 - Homo sapiens cDNA FLJ10310 fis, clone NT2RM2000322, highly similar to Homo sapiens mRNA for KIAA0859 protein.BC006814 - Homo sapiens methyltransferase like 13, mRNA (cDNA clone IMAGE:3448012), partial cds.AK124482 - Homo sapiens cDNA FLJ42491 fis, clone BRACE2033394.AK094818 - Homo sapiens cDNA FLJ37499 fis, clone BRAWH2016106.JD511643 - Sequence 492667 from Patent EP1572962.JD361291 - Sequence 342315 from Patent EP1572962.JD150998 - Sequence 132022 from Patent EP1572962.JD432110 - Sequence 413134 from Patent EP1572962.JD311041 - Sequence 292065 from Patent EP1572962.JD359760 - Sequence 340784 from Patent EP1572962.JD324377 - Sequence 305401 from Patent EP1572962.JD414429 - Sequence 395453 from Patent EP1572962.JD227358 - Sequence 208382 from Patent EP1572962.JD327303 - Sequence 308327 from Patent EP1572962.JD272241 - Sequence 253265 from Patent EP1572962.JD347620 - Sequence 328644 from Patent EP1572962.JD349250 - Sequence 330274 from Patent EP1572962.JD348986 - Sequence 330010 from Patent EP1572962.JD358786 - Sequence 339810 from Patent EP1572962.JD358765 - Sequence 339789 from Patent EP1572962.JD378903 - Sequence 359927 from Patent EP1572962.JD296209 - Sequence 277233 from Patent EP1572962.JD472842 - Sequence 453866 from Patent EP1572962.JD103475 - Sequence 84499 from Patent EP1572962.JD170931 - Sequence 151955 from Patent EP1572962.JD503884 - Sequence 484908 from Patent EP1572962.JD041104 - Sequence 22128 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A6NFK0, A8K6S5, CGI-01, KIAA0859, MET13_HUMAN, METTL13, NM_015935, NP_055770, O94940, Q53EZ6, Q5TGP9, Q5TGQ0, Q8N2P8, Q8N6R0, Q96J11, Q96SQ0, Q9Y2Z1, Q9Y3M6UCSC ID: uc001ghz.3RefSeq Accession: NM_015935
Protein: Q8N6R0
(aka MET13_HUMAN)
CCDS: CCDS1299.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_015935.4
exon count:
8 CDS single in 3' UTR:
no
RNA size:
3421
ORF size:
2100 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4307.00 frame shift in genome:
no
% Coverage:
99.59
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
yes
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
367 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.