Human Gene PMS2P5 (uc003ubl.2) Description and Page Index
Description: Homo sapiens postmeiotic segregation increased 2 pseudogene 5 (PMS2P5), transcript variant 1, non-coding RNA.
Transcript (Including UTRs)
Position: hg19 chr7:74,306,894-74,322,330 Size: 15,437 Total Exon Count: 7 Strand: +
Position: hg19 chr7:74,310,333-74,321,779 Size: 11,447 Coding Exon Count: 6
Data last updated: 2013-06-14
Sequence and Links to Tools and Databases
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR003594 - ATPase-like_ATP-bd
IPR002099 - DNA_mismatch_repair
IPR014762 - DNA_mismatch_repair_CS
Pfam Domains: PF07661 - MORN repeat variant
PF13589 - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SCOP Domains: 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
ModBase Predicted Comparative 3D Structure on Q15157
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC052588 - Homo sapiens postmeiotic segregation increased 2-like 5, mRNA (cDNA clone IMAGE:6255019), partial cds. BC027480 - Homo sapiens cDNA clone IMAGE:4397924, **** WARNING: chimeric clone ****. D38436 - Homo sapiens hPMS4 mRNA, partial cds. D38502 - Homo sapiens PMS4 mRNA (yeast mismatch repair gene PMS1 homologue), partial cds (C-terminal region). E11277 - Human cDNA encoding mismatch repair-related protein. AK309660 - Homo sapiens cDNA, FLJ99701. D38439 - Homo sapiens hPMS7 mRNA, partial cds. D38501 - Homo sapiens PMS7 mRNA (yeast mismatch repair gene PMS1 homologue), partial cds (C-terminal region). E11280 - Human cDNA encoding mismatch repair-related protein. AB528779 - Synthetic construct DNA, clone: pF1KE0244, Homo sapiens PMS2L5 gene for postmeiotic segregation increased 2-like protein 5, without stop codon, in Flexi system. BC152850 - Synthetic construct Homo sapiens clone IMAGE:100016062, MGC:184207 postmeiotic segregation increased 2-like 5 (PMS2L5) mRNA, encodes complete protein. JD070874 - Sequence 51898 from Patent EP1572962. JD447983 - Sequence 429007 from Patent EP1572962. JD316586 - Sequence 297610 from Patent EP1572962. JD538559 - Sequence 519583 from Patent EP1572962. JD538295 - Sequence 519319 from Patent EP1572962. DQ573916 - Homo sapiens piRNA piR-42028, complete sequence. JD044060 - Sequence 25084 from Patent EP1572962. JD175469 - Sequence 156493 from Patent EP1572962. DQ584291 - Homo sapiens piRNA piR-51403, complete sequence. DQ577017 - Homo sapiens piRNA piR-45129, complete sequence. DQ595418 - Homo sapiens piRNA piR-61530, complete sequence. JD304835 - Sequence 285859 from Patent EP1572962. JD415816 - Sequence 396840 from Patent EP1572962. JD256086 - Sequence 237110 from Patent EP1572962. DQ596866 - Homo sapiens piRNA piR-34932, complete sequence. JD489553 - Sequence 470577 from Patent EP1572962. JD525835 - Sequence 506859 from Patent EP1572962. JD399050 - Sequence 380074 from Patent EP1572962. DQ586658 - Homo sapiens piRNA piR-53770, complete sequence. JD311453 - Sequence 292477 from Patent EP1572962. JD491817 - Sequence 472841 from Patent EP1572962. JD062864 - Sequence 43888 from Patent EP1572962. JD299630 - Sequence 280654 from Patent EP1572962. JD487137 - Sequence 468161 from Patent EP1572962. JD118182 - Sequence 99206 from Patent EP1572962. DQ586947 - Homo sapiens piRNA piR-54059, complete sequence. JD144181 - Sequence 125205 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: hPMS4, NR_027775, PMS2L5, PMS4, Q15157, Q15157_HUMAN UCSC ID: uc003ubl.2 RefSeq Accession: NR_027775
Gene Model Information
7 CDS single in 3' UTR:
600 CDS single in intron:
Alignment % ID:
800.00 frame shift in genome:
has start codon:
stop codon in genome:
# of Alignments:
has end codon:
# AT/AC introns
end bleed into intron:
0 # strange splices:
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.