Human Gene CCDC77 (uc001qig.3) Description and Page Index
  Description: Homo sapiens coiled-coil domain containing 77 (CCDC77), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:510,741-551,806 Size: 41,066 Total Exon Count: 13 Strand: +
Coding Region
   Position: hg19 chr12:518,550-551,086 Size: 32,537 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:510,741-551,806)mRNA (may differ from genome)Protein (488 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: CCD77_HUMAN
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 77;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.84 RPKM in Testis
Total median expression: 132.65 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -55.06180-0.306 Picture PostScript Text
3' UTR -213.41720-0.296 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9BR77
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005813 centrosome
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  AK316029 - Homo sapiens cDNA, FLJ78928 complete cds.
AK308216 - Homo sapiens cDNA, FLJ98164.
LF384183 - JP 2014500723-A/191686: Polycomb-Associated Non-Coding RNAs.
AK293165 - Homo sapiens cDNA FLJ58763 complete cds.
AK027638 - Homo sapiens cDNA FLJ14732 fis, clone NT2RP3001969, weakly similar to TRICHOHYALIN.
BC006444 - Homo sapiens coiled-coil domain containing 77, mRNA (cDNA clone MGC:13183 IMAGE:3616619), complete cds.
MA619760 - JP 2018138019-A/191686: Polycomb-Associated Non-Coding RNAs.
LF365597 - JP 2014500723-A/173100: Polycomb-Associated Non-Coding RNAs.
LF365595 - JP 2014500723-A/173098: Polycomb-Associated Non-Coding RNAs.
LF365594 - JP 2014500723-A/173097: Polycomb-Associated Non-Coding RNAs.
MA601174 - JP 2018138019-A/173100: Polycomb-Associated Non-Coding RNAs.
MA601172 - JP 2018138019-A/173098: Polycomb-Associated Non-Coding RNAs.
MA601171 - JP 2018138019-A/173097: Polycomb-Associated Non-Coding RNAs.
LF365593 - JP 2014500723-A/173096: Polycomb-Associated Non-Coding RNAs.
LF365590 - JP 2014500723-A/173093: Polycomb-Associated Non-Coding RNAs.
LF365588 - JP 2014500723-A/173091: Polycomb-Associated Non-Coding RNAs.
LF365585 - JP 2014500723-A/173088: Polycomb-Associated Non-Coding RNAs.
LF365584 - JP 2014500723-A/173087: Polycomb-Associated Non-Coding RNAs.
LF365582 - JP 2014500723-A/173085: Polycomb-Associated Non-Coding RNAs.
LF365581 - JP 2014500723-A/173084: Polycomb-Associated Non-Coding RNAs.
JD353580 - Sequence 334604 from Patent EP1572962.
JD038756 - Sequence 19780 from Patent EP1572962.
JD345806 - Sequence 326830 from Patent EP1572962.
JD453986 - Sequence 435010 from Patent EP1572962.
JD512958 - Sequence 493982 from Patent EP1572962.
JD204522 - Sequence 185546 from Patent EP1572962.
JD473374 - Sequence 454398 from Patent EP1572962.
MA601170 - JP 2018138019-A/173096: Polycomb-Associated Non-Coding RNAs.
MA601167 - JP 2018138019-A/173093: Polycomb-Associated Non-Coding RNAs.
MA601165 - JP 2018138019-A/173091: Polycomb-Associated Non-Coding RNAs.
MA601162 - JP 2018138019-A/173088: Polycomb-Associated Non-Coding RNAs.
MA601161 - JP 2018138019-A/173087: Polycomb-Associated Non-Coding RNAs.
MA601159 - JP 2018138019-A/173085: Polycomb-Associated Non-Coding RNAs.
MA601158 - JP 2018138019-A/173084: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DDE8, CCD77_HUMAN, NM_032358, NP_001123620, Q9BR77
UCSC ID: uc001qig.3
RefSeq Accession: NM_032358
Protein: Q9BR77 (aka CCD77_HUMAN)
CCDS: CCDS8503.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_032358.3
exon count: 13CDS single in 3' UTR: no RNA size: 2386
ORF size: 1467CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2964.00frame shift in genome: no % Coverage: 99.20
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.