Human Gene OXNAD1 (uc003caw.3)
Description: Homo sapiens oxidoreductase NAD-binding domain containing 1 (OXNAD1), mRNA.
Transcript (Including UTRs)
Position: hg19 chr3:16,306,667-16,347,594 Size: 40,928 Total Exon Count: 9 Strand: +
Coding Region
Position: hg19 chr3:16,312,460-16,345,069 Size: 32,610 Coding Exon Count: 7
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: OXND1_HUMAN
DESCRIPTION: RecName: Full=Oxidoreductase NAD-binding domain-containing protein 1; EC=1.-.-.-; Flags: Precursor;
SIMILARITY: Contains 1 FAD-binding FR-type domain.
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): OXNAD1
CDC HuGE Published Literature: OXNAD1
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR017927 - Fd_Rdtase_FAD-bd
IPR001433 - OxRdtase_FAD/NAD-bd
IPR001221 - Phe_hydroxylase
IPR017938 - Riboflavin_synthase-like_b-brl
Pfam Domains: PF00175 - Oxidoreductase NAD-binding domain
PF08030 - Ferric reductase NAD binding domain
SCOP Domains: 63380 - Riboflavin synthase domain-like
52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
ModBase Predicted Comparative 3D Structure on Q96HP4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
DQ364598 - Homo sapiens oxidoreductase NAD-binding domain-containing 1 variant mRNA, complete cds.AK307258 - Homo sapiens cDNA, FLJ97206.BC008322 - Homo sapiens oxidoreductase NAD-binding domain containing 1, mRNA (cDNA clone MGC:15763 IMAGE:3358042), complete cds.JD337343 - Sequence 318367 from Patent EP1572962.JD199009 - Sequence 180033 from Patent EP1572962.JD220605 - Sequence 201629 from Patent EP1572962.JD162777 - Sequence 143801 from Patent EP1572962.JD359224 - Sequence 340248 from Patent EP1572962.JD493540 - Sequence 474564 from Patent EP1572962.JD250763 - Sequence 231787 from Patent EP1572962.AK298829 - Homo sapiens cDNA FLJ54836 complete cds.JD257776 - Sequence 238800 from Patent EP1572962.AB529111 - Synthetic construct DNA, clone: pF1KB4671, Homo sapiens OXNAD1 gene for oxidoreductase NAD-binding domain containing protein 1, without stop codon, in Flexi system.HQ448162 - Synthetic construct Homo sapiens clone IMAGE:100071549; CCSB005302_01 oxidoreductase NAD-binding domain containing 1 (OXNAD1) gene, encodes complete protein.KJ895175 - Synthetic construct Homo sapiens clone ccsbBroadEn_04569 OXNAD1 gene, encodes complete protein.AB209556 - Homo sapiens mRNA for hypothetical protein BC008322 variant protein.AL832787 - Homo sapiens mRNA; cDNA DKFZp667E0423 (from clone DKFZp667E0423).JD053351 - Sequence 34375 from Patent EP1572962.DQ588616 - Homo sapiens piRNA piR-55728, complete sequence.BC007285 - Homo sapiens oxidoreductase NAD-binding domain containing 1, mRNA (cDNA clone IMAGE:3344267).BC018770 - Homo sapiens oxidoreductase NAD-binding domain containing 1, mRNA (cDNA clone IMAGE:4649198), with apparent retained intron.
Other Names for This Gene
Alternate Gene Symbols: NM_138381, NP_612390, OXND1_HUMAN, Q2HYC7, Q59FA4, Q96HP4UCSC ID: uc003caw.3RefSeq Accession: NM_138381
Protein: Q96HP4
(aka OXND1_HUMAN)
CCDS: CCDS2630.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_138381.3
exon count:
9 CDS single in 3' UTR:
no
RNA size:
3992
ORF size:
939 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1819.50 frame shift in genome:
no
% Coverage:
99.40
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
2495 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.