Human Gene CCDC64B (uc002ctf.4) Description and Page Index
  Description: Homo sapiens coiled-coil domain containing 64B (CCDC64B), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr16:3,077,868-3,085,542 Size: 7,675 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg19 chr16:3,078,107-3,085,497 Size: 7,391 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:3,077,868-3,085,542)mRNA (may differ from genome)Protein (508 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
neXtProtOMIMPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Bicaudal D-related protein 2; Short=BICD-related protein 2; Short=BICDR-2; AltName: Full=Coiled-coil domain-containing protein 64B;
SUBUNIT: Interacts with RAB13 (By similarity).
SIMILARITY: Belongs to the BICDR family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 55.87 RPKM in Esophagus - Mucosa
Total median expression: 339.30 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -15.9045-0.353 Picture PostScript Text
3' UTR -106.10239-0.444 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on A1A5D9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 Protein SequenceProtein Sequence   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0017137 Rab GTPase binding

-  Descriptions from all associated GenBank mRNAs
  AL833717 - Homo sapiens mRNA; cDNA DKFZp666A165 (from clone DKFZp666A165).
AL833749 - Homo sapiens mRNA; cDNA DKFZp666L166 (from clone DKFZp666L166).
BC015446 - Homo sapiens hypothetical LOC146439, mRNA (cDNA clone IMAGE:4425111), partial cds.
BC128602 - Homo sapiens coiled-coil domain containing 64B, mRNA (cDNA clone MGC:158069 IMAGE:40132962), complete cds.
KJ900233 - Synthetic construct Homo sapiens clone ccsbBroadEn_09627 CCDC64B gene, encodes complete protein.
AK307181 - Homo sapiens cDNA, FLJ97129.
JD321334 - Sequence 302358 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A1A5D9, BICDR2, BICR2_HUMAN, NM_001103175, NP_001096645, Q658L9
UCSC ID: uc002ctf.4
RefSeq Accession: NM_001103175
Protein: A1A5D9 (aka BICR2_HUMAN)
CCDS: CCDS45393.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001103175.1
exon count: 9CDS single in 3' UTR: no RNA size: 1811
ORF size: 1527CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3247.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.