Human Gene HGH1 (uc010mfs.3)
  Description: Homo sapiens family with sequence similarity 203, member A (HGH1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr8:145,192,672-145,195,620 Size: 2,949 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr8:145,192,739-145,194,455 Size: 1,717 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:145,192,672-145,195,620)mRNA (may differ from genome)Protein (390 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHPRDLynxMGIneXtProtPubMed
TreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: F203A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM203A; AltName: Full=Brain protein 16;
SIMILARITY: Belongs to the FAM203 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.83 RPKM in Testis
Total median expression: 19.03 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -31.2067-0.466 Picture PostScript Text
3' UTR -466.761165-0.401 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011989 - ARM-like
IPR016024 - ARM-type_fold
IPR007206 - FAM203_C
IPR007205 - FAM203_N

Pfam Domains:
PF04063 - Domain of unknown function (DUF383)
PF04064 - Domain of unknown function (DUF384)

SCOP Domains:
48371 - ARM repeat

ModBase Predicted Comparative 3D Structure on Q9BTY7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0008150 biological_process

Cellular Component:
GO:0005575 cellular_component


-  Descriptions from all associated GenBank mRNAs
  LF210329 - JP 2014500723-A/17832: Polycomb-Associated Non-Coding RNAs.
BC003035 - Homo sapiens chromosome 8 open reading frame 30A, mRNA (cDNA clone MGC:4355 IMAGE:2822563), complete cds.
BC009915 - Homo sapiens chromosome 8 open reading frame 30A, mRNA (cDNA clone MGC:2733 IMAGE:2822563), complete cds.
AK098226 - Homo sapiens cDNA FLJ40907 fis, clone UTERU2005050.
BC015471 - Homo sapiens chromosome 8 open reading frame 30A, mRNA (cDNA clone IMAGE:3845929), partial cds.
AF151022 - Homo sapiens HSPC188 mRNA, complete cds.
JD216628 - Sequence 197652 from Patent EP1572962.
JD390853 - Sequence 371877 from Patent EP1572962.
JD535784 - Sequence 516808 from Patent EP1572962.
JD074627 - Sequence 55651 from Patent EP1572962.
JD109381 - Sequence 90405 from Patent EP1572962.
JD537473 - Sequence 518497 from Patent EP1572962.
JD446739 - Sequence 427763 from Patent EP1572962.
JD207297 - Sequence 188321 from Patent EP1572962.
JD456068 - Sequence 437092 from Patent EP1572962.
JD433801 - Sequence 414825 from Patent EP1572962.
JD123081 - Sequence 104105 from Patent EP1572962.
JD123898 - Sequence 104922 from Patent EP1572962.
JD349377 - Sequence 330401 from Patent EP1572962.
JD366896 - Sequence 347920 from Patent EP1572962.
JD519959 - Sequence 500983 from Patent EP1572962.
JD500316 - Sequence 481340 from Patent EP1572962.
JD392488 - Sequence 373512 from Patent EP1572962.
JD401130 - Sequence 382154 from Patent EP1572962.
JD403497 - Sequence 384521 from Patent EP1572962.
DQ573451 - Homo sapiens piRNA piR-41563, complete sequence.
JD231120 - Sequence 212144 from Patent EP1572962.
JD337325 - Sequence 318349 from Patent EP1572962.
JD492603 - Sequence 473627 from Patent EP1572962.
JD429217 - Sequence 410241 from Patent EP1572962.
JD132294 - Sequence 113318 from Patent EP1572962.
JD130905 - Sequence 111929 from Patent EP1572962.
JD335166 - Sequence 316190 from Patent EP1572962.
JD137282 - Sequence 118306 from Patent EP1572962.
JD157016 - Sequence 138040 from Patent EP1572962.
JD164095 - Sequence 145119 from Patent EP1572962.
JD420387 - Sequence 401411 from Patent EP1572962.
JD086509 - Sequence 67533 from Patent EP1572962.
JD159281 - Sequence 140305 from Patent EP1572962.
JD210505 - Sequence 191529 from Patent EP1572962.
JD339968 - Sequence 320992 from Patent EP1572962.
JD459097 - Sequence 440121 from Patent EP1572962.
JD518943 - Sequence 499967 from Patent EP1572962.
JD448643 - Sequence 429667 from Patent EP1572962.
MA445906 - JP 2018138019-A/17832: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: BRP16, C8orf30A, F203A_HUMAN, FAM203A, NM_016458, NP_057542, Q9BTY7
UCSC ID: uc010mfs.3
RefSeq Accession: NM_016458
Protein: Q9BTY7 (aka F203A_HUMAN)
CCDS: CCDS6417.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_016458.2
exon count: 6CDS single in 3' UTR: no RNA size: 2441
ORF size: 1173CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2546.00frame shift in genome: no % Coverage: 98.53
has start codon: yes stop codon in genome: no # of Alignments: 2
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 521# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.