Human Gene C1orf122 (uc001ccd.2)
Description: Homo sapiens chromosome 1 open reading frame 122 (C1orf122), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:38,273,473-38,275,126 Size: 1,654 Total Exon Count: 3 Strand: +
Coding Region
Position: hg19 chr1:38,274,077-38,274,745 Size: 669 Coding Exon Count: 3
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CA122_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C1orf122; AltName: Full=Protein ALAESM;
SEQUENCE CAUTION: Sequence=AAH57819.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAC86950.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=CAH70085.1; Type=Erroneous translation; Note=Wrong choice of CDS;
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): C1orf122
CDC HuGE Published Literature: C1orf122
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF15855 - Domain of unknown function (DUF4726)
ModBase Predicted Comparative 3D Structure on Q6ZSJ8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
LF385425 - JP 2014500723-A/192928: Polycomb-Associated Non-Coding RNAs.LF206608 - JP 2014500723-A/14111: Polycomb-Associated Non-Coding RNAs.BC016402 - Homo sapiens, clone IMAGE:4177569, mRNA.MA621002 - JP 2018138019-A/192928: Polycomb-Associated Non-Coding RNAs.MA442185 - JP 2018138019-A/14111: Polycomb-Associated Non-Coding RNAs.JD275098 - Sequence 256122 from Patent EP1572962.AY517499 - Homo sapiens hypothetical protein ALAESM mRNA, complete cds.JD111516 - Sequence 92540 from Patent EP1572962.JD163875 - Sequence 144899 from Patent EP1572962.LF206607 - JP 2014500723-A/14110: Polycomb-Associated Non-Coding RNAs.JD325357 - Sequence 306381 from Patent EP1572962.LF356531 - JP 2014500723-A/164034: Polycomb-Associated Non-Coding RNAs.BC107856 - Homo sapiens chromosome 1 open reading frame 122, mRNA (cDNA clone IMAGE:5239581).LF213509 - JP 2014500723-A/21012: Polycomb-Associated Non-Coding RNAs.BC057819 - Homo sapiens chromosome 1 open reading frame 122, mRNA (cDNA clone MGC:71776 IMAGE:4792982), complete cds.AK127381 - Homo sapiens cDNA FLJ45459 fis, clone BRSTN2010416.BC127187 - Homo sapiens chromosome 1 open reading frame 122, mRNA (cDNA clone IMAGE:40035129), partial cds.BC102041 - Homo sapiens cDNA clone IMAGE:40035904, partial cds.BC127188 - Homo sapiens chromosome 1 open reading frame 122, mRNA (cDNA clone IMAGE:40035130), partial cds.BC141938 - Homo sapiens cDNA clone IMAGE:40035905, partial cds.LF356530 - JP 2014500723-A/164033: Polycomb-Associated Non-Coding RNAs.JD217629 - Sequence 198653 from Patent EP1572962.KJ903738 - Synthetic construct Homo sapiens clone ccsbBroadEn_13132 C1orf122 gene, encodes complete protein.LF356529 - JP 2014500723-A/164032: Polycomb-Associated Non-Coding RNAs.JD374735 - Sequence 355759 from Patent EP1572962.JD344995 - Sequence 326019 from Patent EP1572962.JD426880 - Sequence 407904 from Patent EP1572962.JD224818 - Sequence 205842 from Patent EP1572962.JD206315 - Sequence 187339 from Patent EP1572962.JD426786 - Sequence 407810 from Patent EP1572962.JD382889 - Sequence 363913 from Patent EP1572962.JD114582 - Sequence 95606 from Patent EP1572962.MA442184 - JP 2018138019-A/14110: Polycomb-Associated Non-Coding RNAs.MA592108 - JP 2018138019-A/164034: Polycomb-Associated Non-Coding RNAs.MA449086 - JP 2018138019-A/21012: Polycomb-Associated Non-Coding RNAs.MA592107 - JP 2018138019-A/164033: Polycomb-Associated Non-Coding RNAs.MA592106 - JP 2018138019-A/164032: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: A2RQF4, CA122_HUMAN, NM_198446, NP_940848, Q56A71, Q6ZSJ8, uc001ccb.1UCSC ID: uc001ccd.2RefSeq Accession: NM_198446
Protein: Q6ZSJ8
(aka CA122_HUMAN)
CCDS: CCDS427.2
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_198446.2
exon count:
3 CDS single in 3' UTR:
no
RNA size:
1359
ORF size:
333 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1115.00 frame shift in genome:
no
% Coverage:
96.98
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.