ID:UDB10_HUMAN DESCRIPTION: RecName: Full=UDP-glucuronosyltransferase 2B10; Short=UDPGT 2B10; EC=22.214.171.124; Flags: Precursor; FUNCTION: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. CATALYTIC ACTIVITY: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. SUBCELLULAR LOCATION: Microsome membrane; Single-pass membrane protein (Potential). Endoplasmic reticulum membrane; Single-pass membrane protein (Potential). SIMILARITY: Belongs to the UDP-glycosyltransferase family.
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): UGT2B10 CDC HuGE Published Literature: UGT2B10
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P36537
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.