Human Gene CTSL3P (uc004apm.1) Description and Page Index
  Description: Homo sapiens cathepsin L family member 3, pseudogene (CTSL3P), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr9:90,387,830-90,401,799 Size: 13,970 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg19 chr9:90,387,836-90,401,799 Size: 13,964 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:90,387,830-90,401,799)mRNA (may differ from genome)Protein (216 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsHGNCLynx
MGIneXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: CATL3_HUMAN
DESCRIPTION: RecName: Full=Putative cathepsin L-like protein 3; AltName: Full=HCTSL-s;
SIMILARITY: Belongs to the peptidase C1 family.
CAUTION: Could be the product of a pseudogene. Lacks the region corresponding to the signal sequence and the propeptide. Has mutations in all 3 active site positions.

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.18 RPKM in Kidney - Cortex
Total median expression: 1.43 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013128 - Peptidase_C1A
IPR013201 - Prot_inhib_I29

SCOP Domains:
54001 - Cysteine proteinases

ModBase Predicted Comparative 3D Structure on Q5NE16
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0008234 cysteine-type peptidase activity

Biological Process:
GO:0006508 proteolysis


-  Descriptions from all associated GenBank mRNAs
  BC160188 - Synthetic construct Homo sapiens clone IMAGE:100064220, MGC:193303 cathepsin L family member 3 (CTSL3) mRNA, encodes complete protein.
AJ851862 - Homo sapiens mRNA for cathepsin L-like protein (HCTSL-s gene).

-  Other Names for This Gene
  Alternate Gene Symbols: CATL3_HUMAN, CTSL3, NR_027917, Q5NE16
UCSC ID: uc004apm.1
RefSeq Accession: NR_027917
Protein: Q5NE16 (aka CATL3_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_027917.1
exon count: 5CDS single in 3' UTR: no RNA size: 657
ORF size: 651CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1353.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.